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Details on Person TYMS gene expression

Class:Id	BlackBoxEvent:8962050
_displayName	TYMS gene expression
_doRelease	TRUE
_timestamp	2017-02-28 16:48:32
authored	[InstanceEdit:113696] Gopinathrao, G, 2004-06-16 19:22:00
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8962045] Orlic-Milacic, Marija, 2017-02-07
edited	[InstanceEdit:8961898] Orlic-Milacic, Marija, 2017-02-06
input	[EntityWithAccessionedSequence:8962047] TYMS gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:141354] Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes
modified	[InstanceEdit:8980637] Orlic-Milacic, Marija, 2017-02-28 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TYMS gene expression
output	[EntityWithAccessionedSequence:73518] TYMS [cytosol] [Homo sapiens]
precedingEvent	[Reaction:69227] Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes [Homo sapiens] [Reaction:8942836] CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 [Homo sapiens] [BlackBoxEvent:9659820] RB1 translocates to the nucleus [Homo sapiens]
regulatedBy	[PositiveRegulation:8962049] Positive regulation by 'E2F1:TFDP1,TFDP2 [nucleoplasm]'
regulationReference	[RegulationReference:9642776] Positive regulation by 'E2F1:TFDP1,TFDP2 [nucleoplasm]' Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes
releaseDate	2009-09-30
reviewed	[InstanceEdit:113697] Bosco, G, 2004-06-16 19:24:21
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:617365] Matthews, L, 2010-04-21
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8962051] R-HSA-8962050.4
summation	[Summation:8962046] Expression of the TYMS gene, encoding thymidylate synthase, ...
(hasEvent)	[Pathway:69205] G1/S-Specific Transcription [Homo sapiens]
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No pathways have been reviewed or authored by TYMS gene expression (8962050)