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Details on Person NSUN5 (NSUN5A) methylates cytidine-3782 of 28S rRNA yielding 5-methylcytidine-3782

Class:IdReaction:8961741
_displayNameNSUN5 (NSUN5A) methylates cytidine-3782 of 28S rRNA yielding 5-methylcytidine-3782
_timestamp2017-08-17 19:51:23
authored[InstanceEdit:8961733] May, Bruce, 2017-02-04
catalystActivity[CatalystActivity:8961735] rRNA (cytosine-C5-)-methyltransferase activity of NSUN5 [nucleoplasm]
catalystActivityReference[CatalystActivityReference:9643480] rRNA (cytosine-C5-)-methyltransferase activity of NSUN5 [nucleoplasm] Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:8961736] May, Bruce, 2017-02-05
edited[InstanceEdit:8961733] May, Bruce, 2017-02-04
goBiologicalProcess[GO_BiologicalProcess:161509] rRNA methylation
inferredFrom
input[EntityWithAccessionedSequence:74978] nascent pre-rRNA transcript [nucleoplasm] [Homo sapiens]
[SimpleEntity:77087] AdoMet [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:6793721] Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively
[LiteratureReference:8849106] Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome
modified[InstanceEdit:8961749] May, Bruce, 2017-02-05
[InstanceEdit:9017341] May, Bruce, 2017-08-17
[InstanceEdit:9643047] Wu, G, 2019-04-04
nameNSUN5 (NSUN5A) methylates cytidine-3782 of 28S rRNA yielding 5-methylcytidine-3782
output[EntityWithAccessionedSequence:8961737] 28S rRNA containing 5-methylC-3782 [nucleoplasm] [Homo sapiens]
[SimpleEntity:77502] AdoHcy [nucleoplasm]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8961743] R-HSA-8961741.1
summation[Summation:8961734] NSUN5 (NSUN5A, WBSCR20) methylates the carbon at the 5th pos...
(hasEvent)[Pathway:6790901] rRNA modification in the nucleus and cytosol [Homo sapiens]
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No pathways have been reviewed or authored by NSUN5 (NSUN5A) methylates cytidine-3782 of 28S rRNA yielding 5-methylcytidine-3782 (8961741)
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