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Details on Person UniProt:P13055-2 Eip75B

Class:Id	ReferenceIsoform:89590
_chainChangeLog	chain:1-1412 added on Fri February 6 2015
_displayName	UniProt:P13055-2 Eip75B
_timestamp	2026-05-15 21:13:16
chain	chain:1-1412
checksum	6F4C21B075443F8C
comment	FUNCTION Implicated in the regulation of ecdysone-triggered gene hierarchies. Probably plays a key role in mediating the regulation of the larval molt by 20-OH-ecdysone.SUBCELLULAR LOCATION In mid instar larvae salivary glands, levels increase during puff stage 1, then remain relatively constant until the premetamorphic pulse of ecdysone at puff stage 5. Levels increase again in late larvae at puff stages 9-10. At puff stage 1 expression is also seen in the gut. Levels are low in the gut, Malpighian tubules, fat body and wing disks between stages 1 and 11.INDUCTION The expression of this protein is developmentally regulated and is correlated with the 20-OH-ecdysone induced activity of puff 75B.SIMILARITY Belongs to the nuclear hormone receptor family. NR1 subfamily.
description	recommendedName: Ecdysone-induced protein 75B, isoform B alternativeName: E75-C alternativeName: Nuclear receptor subfamily 1 group D member 3, isoform B
geneName	Eip75B NR1D3 CG8127
identifier	P13055
isoformParent	[ReferenceGeneProduct:146702] UniProt:P13055 Eip75B [Drosophila melanogaster] [ReferenceGeneProduct:146697] UniProt:P17671 Eip75B [Drosophila melanogaster]
isSequenceChanged	FALSE
keyword	Alternative splicing Developmental protein DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger
modified	[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10 [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:437306] Schmidt, EE [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9862192] Weiser, Joel, 2024-02-26 [InstanceEdit:9909836] Weiser, Joel, 2024-05-14 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 [InstanceEdit:9948485] Weiser, Joel, 2025-05-21 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 [InstanceEdit:9970787] Weiser, Joel, 2025-10-31 [InstanceEdit:9983091] Weiser, Joel, 2026-02-20 [InstanceEdit:9989145] Weiser, Joel, 2026-05-15
name	Eip75B
referenceDatabase	[ReferenceDatabase:2] UniProt
secondaryIdentifier	E75BB_DROME Q9VVM9
sequenceLength	1412
species	[Species:56210] Drosophila melanogaster
variantIdentifier	P13055-2
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No pathways have been reviewed or authored by UniProt:P13055-2 Eip75B (89590)