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Details on Person HPRO (4-hydroxy-L-proline) is oxidized to 1PYR-3OH-5COOH (L-...
| Class:Id | Summation:8955829 |
|---|---|
| _displayName | HPRO (4-hydroxy-L-proline) is oxidized to 1PYR-3OH-5COOH (L-... |
| _timestamp | 2024-11-26 00:03:30 |
| created | [InstanceEdit:8955828] Jassal, Bijay, 2017-01-13 |
| modified | [InstanceEdit:8959528] Jassal, Bijay, 2017-01-26 [InstanceEdit:9929424] D'Eustachio, Peter, 2024-11-26 |
| text | HPRO (4-hydroxy-L-proline) is oxidized to 1PYR-3OH-5COOH (L-1-pyrroline-3-hydroxy-5-carboxylate), coupled to the reduction of FAD to FADH2. Hydroxyproline dehydrogenase (PRODH2) located at the inner mitochondrial membrane mediates this reaction. Whereas PRODH prefers L-Pro as substrate, PRODH2 has a clear preference for HPRO (Summitt et al. 2015). |
| (summation) | [Reaction:8955817] PRODH2 oxidises HPRO to 1PYR-3OH-5COOH [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by HPRO (4-hydroxy-L-proline) is oxidized to 1PYR-3OH-5COOH (L-... (8955829)
