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Details on Person Cytosolic PGP (Glycerol-3-phosphate phosphatase) catalyzes t...
| Class:Id | Summation:8955799 |
|---|---|
| _displayName | Cytosolic PGP (Glycerol-3-phosphate phosphatase) catalyzes t... |
| _timestamp | 2025-01-17 21:24:04 |
| created | [InstanceEdit:8955795] Jassal, Bijay, 2017-01-13 |
| modified | [InstanceEdit:8955806] Jassal, Bijay, 2017-01-13 [InstanceEdit:9935655] D'Eustachio, Peter, 2025-01-17 |
| text | Cytosolic PGP (Glycerol-3-phosphate phosphatase) catalyzes the hydrolysis of G3P (glycerol 3-phosphate) to glycerol and phosphate. This reaction is inferred from the properties of the human enzyme overexpressed in mouse cells (Mugabo et al. 2016). The enzyme is inferred to function as a homodimer with one Mg++ ion bound to each subunit, from the properties of the mouse enzyme (Seifried et al. 2014). Al-Maas et al. (2022a,b) hypothesize that PGP, by dissipating glucose-derived glycerol in the liver and pancreas, may play a role in minimizing the effects of hyperglycemia. In the male gonad, PGP activity may be required for normal spermatogenesis (Oppong et al. 2024). |
| (summation) | [Reaction:8955794] PGP:Mg2+ dimer hydrolyses G3P to glycerol [Homo sapiens] |
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No pathways have been reviewed or authored by Cytosolic PGP (Glycerol-3-phosphate phosphatase) catalyzes t... (8955799)
