Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person LRTOMT transfers Met to DA, forming 3MT

Class:IdReaction:8955010
_displayNameLRTOMT transfers Met to DA, forming 3MT
_doReleaseTRUE
_timestamp2020-03-12 14:15:13
authored[InstanceEdit:8955016] Jassal, Bijay, 2017-01-10
catalystActivity[CatalystActivity:8955008] catechol O-methyltransferase activity of LRTOMT [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:8955016] Jassal, Bijay, 2017-01-10
edited[InstanceEdit:8955016] Jassal, Bijay, 2017-01-10
input[SimpleEntity:159362] DA [cytosol]
[SimpleEntity:71284] AdoMet [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:8955013] A catechol-O-methyltransferase that is essential for auditory function in mice and humans
[LiteratureReference:8955009] Mutations of LRTOMT, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans
modified[InstanceEdit:8955025] Jassal, Bijay, 2017-01-10
[InstanceEdit:8955386] Jassal, Bijay, 2017-01-11
[InstanceEdit:9677995] Jassal, Bijay, 2020-03-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameLRTOMT transfers Met to DA, forming 3MT
output[SimpleEntity:8954997] 3MT [cytosol]
[SimpleEntity:71285] AdoHcy [cytosol]
releaseDate2017-03-27
reviewed[InstanceEdit:8955387] D'Eustachio, Peter, 2017-01-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8955024] R-HSA-8955010.3
summation[Summation:8955005] Transmembrane O-methyltransferase (LRTOMT aka COMT2) catalys...
(hasEvent)[Pathway:379397] Enzymatic degradation of dopamine by COMT [Homo sapiens]
[Pathway:8941514] Orphan 6 events [Homo sapiens]
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