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Details on Person E2F1 gene transcription is inhibited by E2F6

Class:Id	BlackBoxEvent:8953556
_displayName	E2F1 gene transcription is inhibited by E2F6
_doRelease	TRUE
_timestamp	2017-07-27 11:33:33
authored	[InstanceEdit:8954169] Orlic-Milacic, Marija, 2017-01-05
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8953554] Orlic-Milacic, Marija, 2016-12-26
edited	[InstanceEdit:9006102] Orlic-Milacic, Marija, 2017-05-19
input	[EntityWithAccessionedSequence:6798348] E2F1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8953102] A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells
modified	[InstanceEdit:8953583] Orlic-Milacic, Marija, 2016-12-26 [InstanceEdit:8953587] Orlic-Milacic, Marija, 2016-12-26 [InstanceEdit:8953590] Orlic-Milacic, Marija, 2016-12-26 [InstanceEdit:9005635] Orlic-Milacic, Marija, 2017-05-09 [InstanceEdit:9006100] Orlic-Milacic, Marija, 2017-05-12 [InstanceEdit:9006104] Orlic-Milacic, Marija, 2017-05-12 [InstanceEdit:9007270] Orlic-Milacic, Marija, 2017-05-29 [InstanceEdit:9007287] Orlic-Milacic, Marija, 2017-05-29 [InstanceEdit:9007294] Orlic-Milacic, Marija, 2017-05-29 [InstanceEdit:9014237] Orlic-Milacic, Marija, 2017-07-27 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	E2F1 gene transcription is inhibited by E2F6
output	[EntityWithAccessionedSequence:68639] E2F1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:8953452] E2F6.com-1 complex binds the E2F1 gene promoter [Homo sapiens] [Reaction:9007283] CBX3 and PRC1.6 associate with E2F6.com-1 [Homo sapiens] [Reaction:9007220] E2F6:TFDP1/2 binds the E2F1 gene promoter [Homo sapiens] [Reaction:8953111] E2F6 binds TFDP1 [Homo sapiens] [Reaction:8954056] E2F6 binds TFDP2 [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:8953585] Negative gene expression regulation by 'E2F6:TFDP1/2,(E2F6:TFDP1:MGA:MAX:EHMT1:EHMT2:CBX3:PRC1.6) [nucleoplasm]'
regulationReference	[RegulationReference:9642139] Negative gene expression regulation by 'E2F6:TFDP1/2,(E2F6:TFDP1:MGA:MAX:EHMT1:EHMT2:CBX3:PRC1.6) [nucleoplasm]' A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells
releaseDate	2017-09-12
reviewed	[InstanceEdit:9005633] Herlihy, Anna, 2017-05-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8953561] R-HSA-8953556.4
summation	[Summation:8953588] The E2F1 gene transcription is inhibited by binding of E2F6 ...
(hasEvent)	[Pathway:8953750] Transcriptional Regulation by E2F6 [Homo sapiens]
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