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Details on Person SLC38A9 binds Ragulator:Rag dimers

Class:IdReaction:8952716
_displayNameSLC38A9 binds Ragulator:Rag dimers
_doReleaseTRUE
_timestamp2017-03-01 00:52:24
authored[InstanceEdit:8952705] Jassal, Bijay, 2016-12-16
compartment[Compartment:70101] cytosol
[Compartment:17938] lysosomal membrane
created[InstanceEdit:8952705] Jassal, Bijay, 2016-12-16
edited[InstanceEdit:8952705] Jassal, Bijay, 2016-12-16
input[Complex:5653979] Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] [Homo sapiens]
[EntityWithAccessionedSequence:5215938] SLC38A9 [lysosomal membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8952719] SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
[LiteratureReference:8952709] Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1
[LiteratureReference:8952699] Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9
modified[InstanceEdit:8952732] Jassal, Bijay, 2016-12-16
[InstanceEdit:8952733] Jassal, Bijay, 2016-12-16
[InstanceEdit:8955386] Jassal, Bijay, 2017-01-11
[InstanceEdit:8980857] Matthews, Lisa, 2017-03-01
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSLC38A9 binds Ragulator:Rag dimers
output[Complex:8952725] Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] [Homo sapiens]
precedingEvent
releaseDate2017-03-27
reviewed[InstanceEdit:8955387] D'Eustachio, Peter, 2017-01-11
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8952730] R-HSA-8952716.2
summation[Summation:8952734] The sodium-coupled neutral amino acid transporter 9 (SLC38A9...
(hasEvent)[Pathway:165159] MTOR signalling [Homo sapiens]
[Pathway:8941514] Orphan 6 events [Homo sapiens]
(precedingEvent)[Reaction:5653968] Ragulator:Rag dimers:SLC38A9 bind mTORC1 [Homo sapiens]
[Reaction:8952726] SLC38A9 transports L-Arg from lysosomal lumen to cytosol [Homo sapiens]
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No pathways have been reviewed or authored by SLC38A9 binds Ragulator:Rag dimers (8952716)