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Details on Person The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia
| Class:Id | LiteratureReference:8952095 |
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| _displayName | The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia |
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| _timestamp | 2016-12-12 21:30:41 |
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| author | [Person:8952082] Linggi, Bryan
[Person:8952089] Müller-Tidow, Carsten
[Person:8952088] van de Locht, Louis
[Person:3301860] Hu, Ming
[Person:8952084] Nip, John
[Person:8952086] Serve, Hubert
[Person:8952087] Berdel, Wolfgang E
[Person:8952083] van der Reijden, Bert
[Person:8952090] Quelle, Dawn E
[Person:8952091] Rowley, Janet D
[Person:8952093] Cleveland, John
[Person:8952079] Jansen, Joop H
[Person:5690201] Pandolfi, Pier Paolo
[Person:8952080] Hiebert, Scott W |
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| created | [InstanceEdit:8952085] Orlic-Milacic, Marija, 2016-12-12 |
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| journal | Nat. Med. |
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| pages | 743-50 |
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| pubMedIdentifier | 12091906 |
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| title | The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia |
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| volume | 8 |
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| year | 2002 |
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| (literatureReference) | [Complex:8952078] RUNX1:CBFB,(Ac-K94,K171-RUNX3:CBFB:EP300:BRD2):CDKN2A gene [nucleoplasm] [Homo sapiens]
[RegulationReference:9642829] Positive gene expression regulation by 'RUNX1:CBFB,(Ac-K94,K171-RUNX3:CBFB:EP300:BRD2):CDKN2A gene [nucleoplasm]' The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia
[Reaction:8952081] RUNX proteins bind the p14-ARF promoter at the CDKN2A locus [Homo sapiens]
[BlackBoxEvent:8952101] p14-ARF transcription is stimulated by RUNX proteins [Homo sapiens] |
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