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Details on Person Acetylated RUNX3 binds to BRD2

Class:IdReaction:8951977
_displayNameAcetylated RUNX3 binds to BRD2
_doReleaseTRUE
_timestamp2017-01-31 16:55:42
authored[InstanceEdit:8951943] Orlic-Milacic, Marija, 2016-12-12
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:8951980] Orlic-Milacic, Marija, 2016-12-12
edited[InstanceEdit:8959863] Orlic-Milacic, Marija, 2017-01-31
input[Complex:8951959] Ac-K94,K171-RUNX3:CBFB:EP300 [nucleoplasm] [Homo sapiens]
[Complex:8951995] BRD2 homodimer [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8951941] Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
modified[InstanceEdit:8952001] Orlic-Milacic, Marija, 2016-12-12
[InstanceEdit:8952004] Orlic-Milacic, Marija, 2016-12-12
[InstanceEdit:8959882] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:8959887] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:8959889] Orlic-Milacic, Marija, 2017-01-31
[InstanceEdit:9606200] Wu, G, 2018-04-19
[InstanceEdit:9641190] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameAcetylated RUNX3 binds to BRD2
output[Complex:8951976] Ac-K94,K171-RUNX3:CBFB:EP300:BRD2 [nucleoplasm] [Homo sapiens]
precedingEvent
regulatedBy[PositiveRegulation:8951981] Positive regulation by 'KRAS:GTP [plasma membrane]'
regulationReference[RegulationReference:9642092] Positive regulation by 'KRAS:GTP [plasma membrane]' Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
releaseDate2017-03-27
reviewed[InstanceEdit:8959885] Ito, Yoshiaki, 2017-01-31
[InstanceEdit:8959883] Chuang, Linda Shyue Huey, 2017-01-31
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8951985] R-HSA-8951977.4
summation[Summation:8952002] RUNX3 acetylated on lysine residues K94 and K171 binds to BR...
(hasEvent)[Pathway:8951936] RUNX3 regulates p14-ARF [Homo sapiens]
(precedingEvent)[Reaction:8952058] CCND1 binds RUNX3 and displaces EP300 [Homo sapiens]
[Reaction:8952081] RUNX proteins bind the p14-ARF promoter at the CDKN2A locus [Homo sapiens]
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No pathways have been reviewed or authored by Acetylated RUNX3 binds to BRD2 (8951977)