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Details on Person A role for IL-27p28 as an antagonist of gp130-mediated signaling

Class:IdLiteratureReference:8950773
_displayNameA role for IL-27p28 as an antagonist of gp130-mediated signaling
_timestamp2018-07-11 19:58:42
author[Person:8950265] Stumhofer, Jason S
[Person:8950687] Tait, Elia D
[Person:8950273] Quinn, William J
[Person:8950557] Hosken, Nancy
[Person:8950294] Spudy, Björn
[Person:8950775] Goenka, Radhika
[Person:8950588] Fielding, Ceri A
[Person:8950315] O'Hara, Aisling C
[Person:5577096] Chen, Yi
[Person:8949796] Jones, Michael L
[Person:8950174] Saris, Christiaan J M
[Person:452407] Rose-John, Stefan
[Person:2426420] Cua, Daniel J
[Person:8950277] Jones, Simon A
[Person:8950419] Elloso, Merle M
[Person:3215085] Grötzinger, Joachim
[Person:8950648] Cancro, Michael P
[Person:5678557] Levin, Steven D
[Person:6809150] Hunter, Christopher A
created[InstanceEdit:8950688] Duenas, Corina, 2016-12-02
journalNat. Immunol.
modified[InstanceEdit:9613061] D'Eustachio, Peter, 2018-07-11
pages1119-26
pubMedIdentifier21057510
titleA role for IL-27p28 as an antagonist of gp130-mediated signaling
volume11
year2010
(literatureReference)[BlackBoxEvent:8950248] Interleukin 27 translocates to the extracellular region [Mus musculus]
[BlackBoxEvent:8951289] Expression of Interferon regulatory factor 1 [Homo sapiens]
[RegulationReference:9642281] Negative regulation by 'IL27 [extracellular region]' A role for IL-27p28 as an antagonist of gp130-mediated signaling
[RegulationReference:9642875] Positive regulation by 'Y963-STAT4 dimer [nucleoplasm]' A role for IL-27p28 as an antagonist of gp130-mediated signaling
[Summation:8950515] Experiments where cells were transfected with mouse Interleu...
[Summation:8950655] Inferred from mouse:
Experiments in cells transfected with m...

[Summation:8951242] STAT4 is phosphorylated at Tyr693. the ability of IL-12 to p...
[Summation:8951306] IRF1 gene is transcribed and translated to IRF1(KA Fitzgerar...
[EntityWithAccessionedSequence:8950293] Il27 [extracellular region] [Mus musculus]
[EntityWithAccessionedSequence:8950713] Il27 [cytosol] [Mus musculus]
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No pathways have been reviewed or authored by A role for IL-27p28 as an antagonist of gp130-mediated signaling (8950773)