Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person Inferred from mouse :
Signal transducer and activator of ...
| Class:Id | Summation:8950715 |
|---|---|
| _displayName | Inferred from mouse : Signal transducer and activator of ... |
| _timestamp | 2017-05-24 16:05:52 |
| created | [InstanceEdit:8950688] Duenas, Corina, 2016-12-02 |
| literatureReference | [LiteratureReference:8950266] New activation modus of STAT3: a tyrosine-less region of the interleukin-22 receptor recruits STAT3 by interacting with its coiled-coil domain [LiteratureReference:8950720] Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor |
| modified | [InstanceEdit:9006625] Jupe, Steve, 2017-05-17 [InstanceEdit:9006961] Jupe, Steve, 2017-05-24 |
| text | Inferred from mouse : Signal transducer and activator of transcription 3 (STAT3) binds tyrosine residues of the Interleukin-23 receptor (IL23R) after cytokine-receptor interaction (Dumoutier et al. 2009, Floss et al. 2013). This is a black box event because STAT3 binding as a consequence of Interleukin-23 stimulation has not been directly demonstrated. IL23R can also bind STAT4, this alternative binding is not represented here only because the evidence for STAT3 binding is inferred from mouse/human chimeras while STAT4 binding evidence was obtained with human protein data. |
| (summation) | [BlackBoxEvent:8950583] STAT3 binds to p-Y-IL23R in IL23:IL23 receptor [Homo sapiens] |
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Signal transducer and activator of ... (8950715)
Signal transducer and activator of ... (8950715)
