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Details on Person Experiments show the presence of nuclear phosphorylated Sign...
| Class:Id | Summation:8950360 |
|---|---|
| _displayName | Experiments show the presence of nuclear phosphorylated Sign... |
| _timestamp | 2017-05-18 13:28:59 |
| created | [InstanceEdit:8950688] Duenas, Corina, 2016-12-02 |
| literatureReference | [LiteratureReference:8950744] Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity [LiteratureReference:8950197] Interleukin-27 induces a STAT1/3- and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes |
| modified | [InstanceEdit:9006617] Jupe, Steve, 2017-05-17 [InstanceEdit:9006733] Duenas, Corina, 2017-05-18 |
| text | Experiments show the presence of nuclear phosphorylated Signal transducer and activator of transcription 1-alpha/beta:Signal transducer and activator of transcription 3 (STAT1:STAT3) heterodimers after activation by Interleukin-6 or Interleukin-27 (Guzzo et al. 2010, Hirahara et al. 2015). This event is presented as a black box event because the exact mechanism of translocation is unknown. |
| (summation) | [BlackBoxEvent:8950733] p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus [Homo sapiens] |
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No pathways have been reviewed or authored by Experiments show the presence of nuclear phosphorylated Sign... (8950360)
