Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane]

Class:IdComplex:8950331
_displayNameIL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane]
_timestamp2016-12-16 16:10:08
compartment[Compartment:876] plasma membrane
created[InstanceEdit:8950688] Duenas, Corina, 2016-12-02
hasComponent
isChimericFALSE
literatureReference[LiteratureReference:8950097] IL-12, IL-23, and IL-27 enhance human beta-defensin-2 production in human keratinocytes
[LiteratureReference:448414] WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
[LiteratureReference:8950165] Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
modified[InstanceEdit:8952742] Duenas, Corina, 2016-12-16
nameIL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8950863] R-HSA-8950331.1
(hasComponent)[Complex:8950267] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] [Homo sapiens]
[Complex:8950779] STAT1:STAT3:IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2 [plasma membrane] [Homo sapiens]
(input)[BlackBoxEvent:8950518] STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex [Homo sapiens]
(output)[BlackBoxEvent:8950340] IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation [Homo sapiens]
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No pathways have been reviewed or authored by IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] (8950331)