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Details on Person Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment

Class:IdLiteratureReference:8950165
_displayNameCutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
_timestamp2016-12-02 11:17:42
author[Person:8950160] Takeda, Atsunobu
[Person:6789750] Hamano, Shinjiro
[Person:8950168] Yamanaka, Atsushi
[Person:8950159] Hanada, Toshikatsu
[Person:8950161] Ishibashi, Tatsuro
[Person:2428863] Mak, Tak W
[Person:112256] Yoshimura, A
[Person:112259] Yoshida, H
created[InstanceEdit:8950156] Duenas, Corina, 2016-12-02
journalJ. Immunol.
pages4886-90
pubMedIdentifier12734330
titleCutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
volume170
year2003
(literatureReference)[BlackBoxEvent:8950340] IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation [Homo sapiens]
[BlackBoxEvent:8950361] Stat1 associates with Il27ra subunit from the Il27:Il27 receptor complex [Mus musculus]
[Reaction:8950409] Il27ra binds Jak1 [Mus musculus]
[Summation:8950206] Signal transducer and activator of transcription 1 (STAT1) a...
[Summation:8950270] Inferred from mouse:
The cytoplasmic domain of Interleuk...

[Summation:8950467] Interleukin 27 phosphorylates/activates Tyrosine protein kin...
[Summation:8950472] There is experimental evidence in Ba/F3 cell lines that Tyro...
[Summation:8950529] Interleukin-27 receptor is formed by Interleukin-27 receptor...
[Summation:8950580] The cytoplasmic domain of Interleukin-27 receptor subunit al...
[Complex:8950155] Il27ra:Jak1 [plasma membrane] [Mus musculus]
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