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Details on Person IL12A:IL12B [endoplasmic reticulum lumen]

Class:Id	Complex:8950122
_displayName	IL12A:IL12B [endoplasmic reticulum lumen]
_timestamp	2016-12-02 11:13:25
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:8950119] Duenas, Corina, 2016-12-02
hasComponent	[EntityWithAccessionedSequence:8950139] IL12A [endoplasmic reticulum lumen] [Homo sapiens] [EntityWithAccessionedSequence:8950126] IL12B [endoplasmic reticulum lumen] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:447201] Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12 [LiteratureReference:8950121] The metallopeptide antibiotic bacitracin inhibits interleukin-12 alphabeta and beta2 secretion [LiteratureReference:8950127] Molecular characterization of interleukin 12
name	IL12A:IL12B Interleukin-12A:Interleukin-12B
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8950147] R-HSA-8950122.1
summation	[Summation:8950124] The Interleukin-12 heterodimer (IL-12) is formed by Interleu...
(input)	[BlackBoxEvent:8950575] IL12A:IL12B translocates from ER lumen to Golgi [Homo sapiens]
(output)	[BlackBoxEvent:8950113] IL12A binds IL12B [Homo sapiens]
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No pathways have been reviewed or authored by IL12A:IL12B [endoplasmic reticulum lumen] (8950122)