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Details on Person FUNDC1 is phosphorylated by ULK1 at Ser17

Class:Id	Reaction:8948146
_displayName	FUNDC1 is phosphorylated by ULK1 at Ser17
_doRelease	TRUE
_timestamp	2020-04-02 10:39:22
authored	[InstanceEdit:8944058] Gillespie, Marc E, 2016-11-01
catalystActivity	[CatalystActivity:8948137] protein serine/threonine kinase activity of ULK1 [mitochondrial outer membrane]
compartment	[Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:8948141] Gillespie, Marc E, 2016-11-10
edited	[InstanceEdit:8980657] Gillespie, Marc E, 2017-02-28
input	[EntityWithAccessionedSequence:8934922] FUNDC1 [mitochondrial outer membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:8934912] ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy
modified	[InstanceEdit:8948153] Gillespie, Marc E, 2016-11-10 [InstanceEdit:8959565] Gillespie, Marc E, 2017-01-26 [InstanceEdit:8959566] Gillespie, Marc E, 2017-01-26 [InstanceEdit:8980022] Gillespie, Marc E, 2017-02-27 [InstanceEdit:8980658] Gillespie, Marc E, 2017-02-28 [InstanceEdit:8980660] Gillespie, Marc E, 2017-02-28 [InstanceEdit:9616354] Gillespie, Marc E, 2018-08-10 [InstanceEdit:9616909] D'Eustachio, Peter, 2018-08-15 [InstanceEdit:9638325] Varusai, Thawfeek, 2019-03-05 [InstanceEdit:9681506] Varusai, Thawfeek, 2020-04-02 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	FUNDC1 is phosphorylated by ULK1 at Ser17
output	[EntityWithAccessionedSequence:8948140] p-S17-FUNDC1 [mitochondrial outer membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:8948136] ULK1 Translocates to the mitochondria [Homo sapiens] [Reaction:8948139] p-S13-FUNDC1 is dephosphorylated by PGAM5 [Homo sapiens] [Reaction:8948039] FUNDC1 is phosphorylated by CK2 [Homo sapiens]
releaseDate	2017-03-27
reviewed	[InstanceEdit:8959558] Feng, Du, 2017-01-26
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9638297] Varusai, Thawfeek, 2019-03-05
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8948151] R-HSA-8948146.5
summation	[Summation:8959564] At mitochondria, ULK1 interacts with FUNDC1, phosphorylating...
(hasEvent)	[Pathway:8934903] Receptor Mediated Mitophagy [Homo sapiens]
(precedingEvent)	[Reaction:8959573] Phosphorylated FUNDC1 links damaged mitochondria to LC3 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779004] Update Tracker - [Reaction:8948146] FUNDC1 is phosphorylated by ULK1 at Ser17 - v66:[addInput, addOutput]
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