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Details on Person mTORC1 phosphorylates MAF1

Class:IdReaction:8944454
_displayNamemTORC1 phosphorylates MAF1
_doReleaseTRUE
_timestamp2017-05-09 14:20:55
authored[InstanceEdit:8948087] Salmena, Leonardo, 2016-08-11
[InstanceEdit:8948082] Carracedo, Arkaitz, 2016-08-11
[InstanceEdit:8944393] Orlic-Milacic, Marija, 2016-11-03
catalystActivity[CatalystActivity:8944450] protein serine/threonine kinase activity of MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane]
compartment[Compartment:70101] cytosol
created[InstanceEdit:8944459] Orlic-Milacic, Marija, 2016-11-03
edited[InstanceEdit:9005630] Orlic-Milacic, Marija, 2017-05-09
input[EntityWithAccessionedSequence:8944460] MAF1 [cytosol] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:8944428] Requirement of the mTOR kinase for the regulation of Maf1 phosphorylation and control of RNA polymerase III-dependent transcription in cancer cells
[LiteratureReference:8944437] mTORC1 directly phosphorylates and regulates human MAF1
modified[InstanceEdit:8959457] Orlic-Milacic, Marija, 2017-01-25
[InstanceEdit:8985729] Orlic-Milacic, Marija, 2017-04-19
[InstanceEdit:9005631] Orlic-Milacic, Marija, 2017-05-09
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namemTORC1 phosphorylates MAF1
output[EntityWithAccessionedSequence:8944455] p-S60,S68,S75-MAF1 [cytosol] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
releaseDate2017-06-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8944463] R-HSA-8944454.2
summation[Summation:8944451] Activated mTORC1 complex phosphorylates the transcription fa...
(hasEvent)[Pathway:8943724] Regulation of PTEN gene transcription [Homo sapiens]
(precedingEvent)[BlackBoxEvent:8944457] MAF1 translocates to the nucleus [Homo sapiens]
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