Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Activated PPARG binds PTEN gene promoter

Class:IdReaction:8944099
_displayNameActivated PPARG binds PTEN gene promoter
_doReleaseTRUE
_timestamp2017-05-09 14:20:50
authored[InstanceEdit:8948087] Salmena, Leonardo, 2016-08-11
[InstanceEdit:8948082] Carracedo, Arkaitz, 2016-08-11
[InstanceEdit:8944098] Orlic-Milacic, Marija, 2016-11-02
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:8944098] Orlic-Milacic, Marija, 2016-11-02
edited[InstanceEdit:9005630] Orlic-Milacic, Marija, 2017-05-09
input[Complex:2026077] PPARG:Fatty Acid Ligand [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:5632949] PTEN gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8943341] Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN
modified[InstanceEdit:8948089] Orlic-Milacic, Marija, 2016-11-10
[InstanceEdit:8959457] Orlic-Milacic, Marija, 2017-01-25
[InstanceEdit:8985729] Orlic-Milacic, Marija, 2017-04-19
[InstanceEdit:9005631] Orlic-Milacic, Marija, 2017-05-09
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActivated PPARG binds PTEN gene promoter
output[Complex:8944097] PPARG:Fatty Acid Ligand:PTEN gene [nucleoplasm] [Homo sapiens]
releaseDate2017-06-12
reviewed[InstanceEdit:8948085] Leslie, Nicholas, 2016-09-30
[InstanceEdit:8948084] Kriplani, Nisha, 2016-09-30
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8944101] R-HSA-8944099.2
summation[Summation:8944100] The nuclear receptor PPARG (PPARgamma), activated by ligand ...
(hasEvent)[Pathway:8943724] Regulation of PTEN gene transcription [Homo sapiens]
(precedingEvent)[BlackBoxEvent:8944104] PTEN gene transcription is stimulated by TP53, EGR1, PPARG, ATF2, MAF1, and inhibited by NR2E1, SALL4, MECOM, SNAI1, SNAI2, JUN [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Activated PPARG binds PTEN gene promoter (8944099)