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Details on Person EGR1 binds the PTEN gene promoter

Class:Id	Reaction:8944078
_displayName	EGR1 binds the PTEN gene promoter
_doRelease	TRUE
_timestamp	2017-05-09 14:20:51
authored	[InstanceEdit:6807125] Orlic-Milacic, Marija, 2015-10-29 [InstanceEdit:8948087] Salmena, Leonardo, 2016-08-11 [InstanceEdit:8948082] Carracedo, Arkaitz, 2016-08-11
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8944081] Orlic-Milacic, Marija, 2016-11-02
edited	[InstanceEdit:9005630] Orlic-Milacic, Marija, 2017-05-09
input	[EntityWithAccessionedSequence:1031703] EGR1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5632949] PTEN gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8943330] The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
modified	[InstanceEdit:8948091] Orlic-Milacic, Marija, 2016-11-10 [InstanceEdit:8959457] Orlic-Milacic, Marija, 2017-01-25 [InstanceEdit:8985729] Orlic-Milacic, Marija, 2017-04-19 [InstanceEdit:9005631] Orlic-Milacic, Marija, 2017-05-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	EGR1 binds the PTEN gene promoter
output	[Complex:8944084] EGR1:PTEN gene [nucleoplasm] [Homo sapiens]
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8944088] R-HSA-8944078.2
summation	[Summation:8944079] In response to UV-induced DNA damage, expresion levels of bo...
(hasEvent)	[Pathway:8943724] Regulation of PTEN gene transcription [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8944082] (delete)PTEN gene transcription is stimualted by EGR1 [Homo sapiens] [BlackBoxEvent:8944104] PTEN gene transcription is stimulated by TP53, EGR1, PPARG, ATF2, MAF1, and inhibited by NR2E1, SALL4, MECOM, SNAI1, SNAI2, JUN [Homo sapiens]
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No pathways have been reviewed or authored by EGR1 binds the PTEN gene promoter (8944078)