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Details on Person MECOM (EVI1) binds the PTEN gene promoter

Class:Id	Reaction:8943811
_displayName	MECOM (EVI1) binds the PTEN gene promoter
_doRelease	TRUE
_timestamp	2017-05-09 14:20:51
authored	[InstanceEdit:8948087] Salmena, Leonardo, 2016-08-11 [InstanceEdit:8948082] Carracedo, Arkaitz, 2016-08-11 [InstanceEdit:8943812] Orlic-Milacic, Marija, 2016-10-30
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8943812] Orlic-Milacic, Marija, 2016-10-30
edited	[InstanceEdit:9005630] Orlic-Milacic, Marija, 2017-05-09
input	[EntityWithAccessionedSequence:8943897] MECOM [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5632949] PTEN gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8942920] Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins
modified	[InstanceEdit:8943899] Orlic-Milacic, Marija, 2016-10-31 [InstanceEdit:8943903] Orlic-Milacic, Marija, 2016-10-31 [InstanceEdit:8948094] Orlic-Milacic, Marija, 2016-11-10 [InstanceEdit:8959457] Orlic-Milacic, Marija, 2017-01-25 [InstanceEdit:8985729] Orlic-Milacic, Marija, 2017-04-19 [InstanceEdit:9005631] Orlic-Milacic, Marija, 2017-05-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MECOM (EVI1) binds the PTEN gene promoter
output	[Complex:8943810] MECOM:PTEN gene [nucleoplasm] [Homo sapiens]
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8943813] R-HSA-8943811.2
summation	[Summation:8943901] The transcription factor MECOM (EVI1) binds the promoter of ...
(hasEvent)	[Pathway:8943724] Regulation of PTEN gene transcription [Homo sapiens]
(precedingEvent)	[Reaction:8943817] MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter [Homo sapiens]
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No pathways have been reviewed or authored by MECOM (EVI1) binds the PTEN gene promoter (8943811)