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Details on Person (delete)PTEN gene transcription is inhibited by SALL4:NuRD

Class:IdBlackBoxEvent:8943804
_displayName(delete)PTEN gene transcription is inhibited by SALL4:NuRD
_doReleaseFALSE
_timestamp2016-11-03 16:25:09
compartment[Compartment:7660] nucleoplasm
[Compartment:70101] cytosol
created[InstanceEdit:8943802] Orlic-Milacic, Marija, 2016-10-29
input[EntityWithAccessionedSequence:5632949] PTEN gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:994203] Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex
[LiteratureReference:8943798] Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex
[LiteratureReference:8942896] SALL4 is a key regulator of survival and apoptosis in human leukemic cells
modified[InstanceEdit:8944206] Orlic-Milacic, Marija, 2016-11-03
name(delete)PTEN gene transcription is inhibited by SALL4:NuRD
output[EntityWithAccessionedSequence:2318746] PTEN mRNA [cytosol] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8943806] R-HSA-8943804.1
summation[Summation:8943803] Binding of the transcription factor SALL4 to the PTEN gene p...
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