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Details on Person SALL4 binds the PTEN gene promoter

Class:Id	Reaction:8943728
_displayName	SALL4 binds the PTEN gene promoter
_doRelease	TRUE
_timestamp	2017-05-09 14:20:54
authored	[InstanceEdit:8948087] Salmena, Leonardo, 2016-08-11 [InstanceEdit:8948082] Carracedo, Arkaitz, 2016-08-11
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8943731] Orlic-Milacic, Marija, 2016-10-28
edited	[InstanceEdit:9005630] Orlic-Milacic, Marija, 2017-05-09
input	[EntityWithAccessionedSequence:452644] SALL4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5632949] PTEN gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8942896] SALL4 is a key regulator of survival and apoptosis in human leukemic cells [LiteratureReference:994203] Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex
modified	[InstanceEdit:8948098] Orlic-Milacic, Marija, 2016-11-10 [InstanceEdit:8959457] Orlic-Milacic, Marija, 2017-01-25 [InstanceEdit:8985729] Orlic-Milacic, Marija, 2017-04-19 [InstanceEdit:9005631] Orlic-Milacic, Marija, 2017-05-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SALL4 binds the PTEN gene promoter
output	[Complex:8943729] SALL4:PTEN gene [nucleoplasm] [Homo sapiens]
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8943732] R-HSA-8943728.2
summation	[Summation:8943730] The transcription factor SALL4 binds the promoter of the PTE...
(hasEvent)	[Pathway:8943724] Regulation of PTEN gene transcription [Homo sapiens]
(precedingEvent)	[Reaction:8943780] SALL4 recruits NuRD to PTEN gene [Homo sapiens]
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No pathways have been reviewed or authored by SALL4 binds the PTEN gene promoter (8943728)