Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells

Class:IdLiteratureReference:8943334
_displayNameUp-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells
_timestamp2016-10-25 10:10:48
author[Person:8943345] Shen, Ying H
[Person:5359456] Zhang, Lin
[Person:8943339] Gan, Yehua
[Person:8943336] Wang, Xinwen
[Person:2684914] Wang, Jian
[Person:8943344] LeMaire, Scott A
[Person:8943340] Coselli, Joseph S
[Person:8943342] Wang, Xing Li
created[InstanceEdit:8943335] Orlic-Milacic, Marija, 2016-10-25
journalJ. Biol. Chem.
pages7727-36
pubMedIdentifier16418168
titleUp-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells
volume281
year2006
(literatureReference)[Complex:8944392] p-T69,T71-ATF2:PTEN gene [nucleoplasm] [Homo sapiens]
[Pathway:6807070] PTEN Regulation [Homo sapiens]
[Pathway:8943724] Regulation of PTEN gene transcription [Homo sapiens]
[BlackBoxEvent:8944104] PTEN gene transcription is stimulated by TP53, EGR1, PPARG, ATF2, MAF1, and inhibited by NR2E1, SALL4, MECOM, SNAI1, SNAI2, JUN [Homo sapiens]
[Reaction:8944397] p-T69,T71-ATF2 binds PTEN gene promoter [Homo sapiens]
[RegulationReference:9642848] Positive gene expression regulation by 'p-T69,T71-ATF2:PTEN gene [nucleoplasm]' Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells
[Change default viewing format]
No pathways have been reviewed or authored by Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endothelial cells (8943334)