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Details on Person Orlic-Milacic, Marija, 2016-10-21
| Class:Id | InstanceEdit:8942965 |
| _displayName | Orlic-Milacic, Marija, 2016-10-21 |
| _timestamp | 2016-10-21 15:56:42 |
| author | [Person:1169272] Orlic-Milacic, Marija |
| dateTime | 2016-10-21 19:56:40 |
| (modified) | [CatalystActivity:199445] phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity of PTEN [cytosol] [Reaction:199456] PTEN dephosphorylates PIP3 [Homo sapiens] [PathwayDiagram:1273430] Diagram of PIP3 activates AKT signaling, Constitutive Signaling by Aberrant PI3K in Cancer, Constitutive Signaling by AKT1 E17K in Cancer, and PTEN Loss of Function in Cancer [BlackBoxEvent:2321904] PTEN mRNA translation negatively regulated by microRNAs [Homo sapiens] [BlackBoxEvent:6807105] Monoubiquitinated PTEN translocates to the nucleus [Homo sapiens] [Reaction:6807106] PTEN undergoes monoubiquitination [Homo sapiens] [Reaction:6807118] USP7 deubiquitinates monoubiquitinated PTEN [Homo sapiens] [Reaction:6807126] Deubiquitinated PTEN translocates to the cytosol [Homo sapiens] [Reaction:6807134] NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN [Homo sapiens] [Reaction:6807206] USP13 and OTUD3 deubiquitinate PTEN [Homo sapiens] |
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No pathways have been reviewed or authored by Orlic-Milacic, Marija, 2016-10-21 (8942965)