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Details on Person Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins
| Class:Id | LiteratureReference:8942920 |
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| _displayName | Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins |
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| _timestamp | 2016-10-20 19:53:48 |
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| author | [Person:8939525] Yoshimi, Akihide
[Person:5634803] Goyama, Susumu
[Person:8939528] Watanabe-Okochi, Naoko
[Person:8942912] Yoshiki, Yumiko
[Person:8942924] Nannya, Yasuhito
[Person:8942901] Nitta, Eriko
[Person:8942925] Arai, Shunya
[Person:8942903] Sato, Tomohiko
[Person:8942916] Shimabe, Munetake
[Person:8939530] Nakagawa, Masahiro
[Person:8942921] Imai, Yoichi
[Person:2730616] Kitamura, Toshio
[Person:5634807] Kurokawa, Mineo |
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| created | [InstanceEdit:8942900] Orlic-Milacic, Marija, 2016-10-20 |
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| journal | Blood |
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| pages | 3617-28 |
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| pubMedIdentifier | 21289308 |
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| title | Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins |
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| volume | 117 |
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| year | 2011 |
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| (literatureReference) | [RegulationReference:9642379] Negative gene expression regulation by 'MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm]' Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins
[Pathway:6807070] PTEN Regulation [Homo sapiens]
[Pathway:8943724] Regulation of PTEN gene transcription [Homo sapiens]
[Reaction:8943811] MECOM (EVI1) binds the PTEN gene promoter [Homo sapiens]
[Reaction:8943817] MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter [Homo sapiens]
[BlackBoxEvent:8944104] PTEN gene transcription is stimulated by TP53, EGR1, PPARG, ATF2, MAF1, and inhibited by NR2E1, SALL4, MECOM, SNAI1, SNAI2, JUN [Homo sapiens]
[Complex:8943810] MECOM:PTEN gene [nucleoplasm] [Homo sapiens]
[Complex:8943820] MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] [Homo sapiens]
[Complex:8943821] MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] [Homo sapiens] |
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No pathways have been reviewed or authored by Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins (8942920)
