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Details on Person N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG

Class:Id	Reaction:8942575
_displayName	N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG
_doRelease	TRUE
_timestamp	2024-11-08 15:22:53
authored	[InstanceEdit:8942587] Jupe, Steve, 2016-10-18
catalystActivity	[CatalystActivity:8942574] N-acetyl-L-aspartate-L-glutamate ligase activity of RIMKLA, RIMKLB [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8942587] Jupe, Steve, 2016-10-18
crossReference	[DatabaseIdentifier:9925784] RHEA:40036
edited	[InstanceEdit:8955635] Jupe, Steve, 2017-01-12
input	[SimpleEntity:29404] L-Glu [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:5693772] NAASP [cytosol]
internalReviewed	[InstanceEdit:9926227] D'Eustachio, Peter, 2024-10-31
isChimeric	FALSE
literatureReference	[LiteratureReference:8942572] Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase
modified	[InstanceEdit:8954511] Jassal, Bijay, 2017-01-09 [InstanceEdit:8955765] Jupe, Steve, 2017-01-13 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9925772] D'Eustachio, Peter, 2024-10-24 [InstanceEdit:9925801] D'Eustachio, Peter, 2024-10-25 [InstanceEdit:9926226] D'Eustachio, Peter, 2024-10-31 [InstanceEdit:9927661] D'Eustachio, Peter, 2024-11-08
name	N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG ATP + L-glutamate + N-acetyl-L-aspartate => ADP + H(+) + N-acetyl-L-aspartyl-L-glutamate + phosphate
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:5693762] NAAG [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:29372] Pi [cytosol]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2017-03-27
reviewed	[InstanceEdit:8955766] Neale, Joseph H, 2017-01-13 [InstanceEdit:9927660] D'Eustachio, Peter, 2024-11-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8942591] R-HSA-8942575.3
structureModified	[InstanceEdit:9925772] D'Eustachio, Peter, 2024-10-24 [InstanceEdit:9925801] D'Eustachio, Peter, 2024-10-25
summation	[Summation:8942567] N-Acetylaspartylglutamate (NAAG) is found at high concentrat...
(hasEvent)	[Pathway:8964539] Glutamate and glutamine metabolism [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9928523] Update Tracker - [Reaction:8942575] N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG - v91:[add_removeInput, removeOutput]
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