Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person ALOXE3 isomerises 12R-HpETE to HXA3

Class:Id	Reaction:8942208
_displayName	ALOXE3 isomerises 12R-HpETE to HXA3
_doRelease	TRUE
_timestamp	2017-01-06 12:18:37
authored	[InstanceEdit:8942205] Jassal, Bijay, 2016-10-11
catalystActivity	[CatalystActivity:8942207] hydroperoxy icosatetraenoate isomerase activity of ALOXE3 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8942205] Jassal, Bijay, 2016-10-11
edited	[InstanceEdit:8942205] Jassal, Bijay, 2016-10-11
input	[SimpleEntity:2142790] 12R-HpETE [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:8942956] The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase [LiteratureReference:8942951] Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope [LiteratureReference:8942949] Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3 [LiteratureReference:8942952] Homozygous ALOXE3 Nonsense Variant Identified in a Patient with Non-Bullous Congenital Ichthyosiform Erythroderma Complicated by Superimposed Bullous Majocchi's Granuloma: The Consequences of Skin Barrier Dysfunction
modified	[InstanceEdit:8942213] Jassal, Bijay, 2016-10-11 [InstanceEdit:8942955] Jassal, Bijay, 2016-10-21 [InstanceEdit:8943298] Jassal, Bijay, 2016-10-25 [InstanceEdit:8954034] Jassal, Bijay, 2017-01-04 [InstanceEdit:8954304] Jassal, Bijay, 2017-01-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ALOXE3 isomerises 12R-HpETE to HXA3
output	[SimpleEntity:8942209] HXA3 [cytosol]
precedingEvent	[Reaction:2161950] Arachidonate is oxidised to 12R-HpETE by ALOX12B [Homo sapiens] [Reaction:428990] SLC27A1 transports arachidonate across the ER membrane [Homo sapiens]
releaseDate	2017-03-27
reviewed	[InstanceEdit:8954302] D'Eustachio, Peter, 2017-01-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8942211] R-HSA-8942208.2
summation	[Summation:8942203] Hydroperoxide isomerase (ALOXE3, e-LOX-3) is a non-heme iron...
(hasEvent)	[Pathway:2142712] Synthesis of 12-eicosatetraenoic acid derivatives [Homo sapiens] [Pathway:8941514] Orphan 6 events [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9919362] Update Tracker - [Reaction:8942208] ALOXE3 isomerises 12R-HpETE to HXA3 - v90:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by ALOXE3 isomerises 12R-HpETE to HXA3 (8942208)