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Query author contributions in Reactome

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Details on Person The ubiquitin E3 ligase RNF170 located on the endoplasmic re...

Class:IdSummation:8942148
_displayNameThe ubiquitin E3 ligase RNF170 located on the endoplasmic re...
_timestamp2016-10-16 12:51:55
created[InstanceEdit:8942152] May, Bruce, 2016-10-08
modified[InstanceEdit:8942484] May, Bruce, 2016-10-16
textThe ubiquitin E3 ligase RNF170 located on the endoplasmic reticulum membrane is recruited by ERLIN1 and ERLIN2 to activated inositol 1,4,5-triphosphate receptors ITPR1 (Lu et al. 2011, Wright et al. 2015). RNF170 also binds the E2-ubiquitin conjugate UBE2D2:Ubiquitin (UbcH5B:Ubiquitin), the substrate for subsequent ubiquitination of ITPR1.
(summation)[Reaction:8939325] RNF170:ERLIN1:ERLIN2 binds ITPR1 (IP(3) receptor) and Ubiquitin:UBE2D2 [Homo sapiens]
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