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Details on Person Superoxide and nitric oxide react to peroxynitrite in the phagosome

Class:Id	Reaction:8942052
_displayName	Superoxide and nitric oxide react to peroxynitrite in the phagosome
_doRelease	TRUE
_timestamp	2018-11-07 00:18:22
authored	[InstanceEdit:9625906] Shamovsky, Veronica, 2018-10-23
compartment	[Compartment:1222282] phagocytic vesicle lumen
created	[InstanceEdit:8942054] Shamovsky, Veronica, 2016-10-07
edited	[InstanceEdit:9625906] Shamovsky, Veronica, 2018-10-23
input	[SimpleEntity:1222461] O2.- [phagocytic vesicle lumen] [SimpleEntity:1222480] NO [phagocytic vesicle lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:1470057] The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide [LiteratureReference:3779404] The reaction of no with superoxide [LiteratureReference:3779403] Peroxynitrite is the major species formed from different flux ratios of co-generated nitric oxide and superoxide: direct reaction with boronate-based fluorescent probe [LiteratureReference:8942055] Peroxynitrite, a potent macrophage-derived oxidizing cytotoxin to combat invading pathogens
modified	[InstanceEdit:8948900] Shamovsky, Veronica, 2016-11-17 [InstanceEdit:9628189] Shamovsky, Veronica, 2018-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Superoxide and nitric oxide react to peroxynitrite in the phagosome
output	[SimpleEntity:8942053] Peroxynitrite [phagocytic vesicle lumen]
precedingEvent	[Reaction:418436] Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) [Homo sapiens] [Reaction:6789092] NOX2 generates superoxide anion from oxygen [Homo sapiens] [Reaction:5668605] RAC2:GTP binds NOX2 complex [Homo sapiens]
releaseDate	2018-12-13
reviewed	[InstanceEdit:2213261] Warner, D, 2012-04-30 [InstanceEdit:9628191] N�sse, Oliver, 2018-11-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8942062] R-HSA-8942052.2
summation	[Summation:8942057] Inside the phagosome, nitric oxide and superoxide react at d...
(hasEvent)	[Pathway:1222556] ROS and RNS production in phagocytes [Homo sapiens]
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No pathways have been reviewed or authored by Superoxide and nitric oxide react to peroxynitrite in the phagosome (8942052)