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Details on Person RUNX2 gene [nucleoplasm]
Class:Id EntityWithAccessionedSequence:8939903
_displayName RUNX2 gene [nucleoplasm]
_timestamp 2016-09-21 19:38:38
compartment [Compartment:7660] nucleoplasm
created [InstanceEdit:8939907] Orlic-Milacic, Marija, 2016-09-21
endCoordinate -1
name RUNX2 gene
referenceEntity [ReferenceDNASequence:8939909] ENSEMBL:ENSG00000124813 RUNX2 [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:8939916] R-HSA-8939903.1
startCoordinate 1
(hasComponent) [Complex:8939910] ESR1:estrogen:RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:8939930] ESRRA:PPARG1CA:RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:8939943] ESRRA:PPARG1CB:RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:8940046] TWIST1:RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:8985291] NKX3-2:RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:9007721] DLX5,(DLX6):RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:9007758] MSX2:RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:9008361] RUNX2-P1:CBFB:RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:9009086] Glucocorticoid ligand:NR3C1:RUNX2 gene [nucleoplasm] [Homo sapiens] [Complex:9016527] RUNX2-P2:CBFB:RUNX2 gene [nucleoplasm] [Homo sapiens]
(input) [BlackBoxEvent:8939900] RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 [Homo sapiens] [Reaction:8939904] Activated ESR1 binds the RUNX2 gene promoter [Homo sapiens] [Reaction:8939929] ESRRA:PPARG1CA binds the RUNX2 gene promoter [Homo sapiens] [Reaction:8939938] ESRRA:PPARG1CB binds the RUNX2 gene promoter [Homo sapiens] [Reaction:8940032] TWIST1 binds the RUNX2 gene promoter [Homo sapiens] [Reaction:8985293] NKX3-2 binds RUNX2 gene promoter [Homo sapiens] [BlackBoxEvent:9007686] RUNX2 gene expression from distal (P1) promoter is inhibited by NKX3-2, MSX2 and RUNX2-P1, and stimulated by DLX5,(DLX6) [Homo sapiens] [Reaction:9007707] DLX5,(DLX6) binds RUNX2 gene promoter [Homo sapiens] [Reaction:9007759] MSX2 binds RUNX2 gene promoter [Homo sapiens] [Reaction:9008345] RUNX2-P1 binds RUNX2 gene promoter [Homo sapiens]
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Pathways
No pathways have been reviewed or authored by RUNX2 gene [nucleoplasm] (8939903)