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Details on Person Transcription of FOXP1 to yield embryonic-specific mRNA

Class:Id	BlackBoxEvent:8939357
_displayName	Transcription of FOXP1 to yield embryonic-specific mRNA
_timestamp	2018-11-20 03:45:38
authored	[InstanceEdit:8939393] May, Bruce, 2016-09-18
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:8939360] May, Bruce, 2016-09-18
edited	[InstanceEdit:8939393] May, Bruce, 2016-09-18
input	[EntityWithAccessionedSequence:8939370] FOXP1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8939361] An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming
modified	[InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9629283] May, Bruce, 2018-11-20 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9733355] Wu, Guanming, 2021-06-04
name	Transcription of FOXP1 to yield embryonic-specific mRNA
output	[EntityWithAccessionedSequence:8939390] FOXP1 mRNA (ES isoform) [cytosol] [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:8939364] Negative gene expression regulation by 'MBNL1,2:FOXP1 gene [nucleoplasm]'
regulationReference	[RegulationReference:9641756] Negative gene expression regulation by 'MBNL1,2:FOXP1 gene [nucleoplasm]' MBNL proteins repress ES-cell-specific alternative splicing and reprogramming
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8939398] R-HSA-8939357.1
summation	[Summation:8939387] The FOXP1 gene is transcribed to yield mRNA. In the mRNA tha... [Summation:8939371] MBNL1 and MBNL2 bind the FOXP1 gene and repress alternative ...
(hasEvent)	[Pathway:452723] Transcriptional regulation of pluripotent stem cells [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8939375] Translation of FOXP1 mRNA (ES-specific isoform) [Homo sapiens]
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