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Details on Person RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation
| Class:Id | LiteratureReference:8939337 |
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| _displayName | RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation |
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| _timestamp | 2016-09-18 06:24:34 |
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| author | [Person:8939311] Lu, Justine P
[Person:8939318] Wang, Yuan
[Person:8939328] Sliter, Danielle A
[Person:8939333] Pearce, Margaret M P
[Person:8939314] Wojcikiewicz, Richard J H |
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| created | [InstanceEdit:8939339] May, Bruce, 2016-09-18 |
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| journal | J. Biol. Chem. |
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| pages | 24426-33 |
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| pubMedIdentifier | 21610068 |
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| title | RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation |
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| volume | 286 |
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| year | 2011 |
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| (literatureReference) | [CatalystActivityReference:9643603] ubiquitin protein ligase activity of RNF170:ERLIN1:ERLIN2:ITPR1:Ub:UBE2D2 [endoplasmic reticulum membrane] RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation
[Complex:8939316] RNF170:ERLIN1:ERLIN2 [endoplasmic reticulum membrane] [Homo sapiens]
[Complex:8939321] RNF170:ERLIN1:ERLIN2:ITPR1:Ub:UBE2D2 [endoplasmic reticulum membrane] [Homo sapiens]
[Reaction:8939325] RNF170:ERLIN1:ERLIN2 binds ITPR1 (IP(3) receptor) and Ubiquitin:UBE2D2 [Homo sapiens]
[BlackBoxEvent:8939326] RNF170 polyubiquitinates ITPR1 (IP3R1, IP(3) receptor) [Homo sapiens] |
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