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Details on Person Wojcikiewicz, Richard J H
| Class:Id | Person:8939314 |
| _displayName | Wojcikiewicz, Richard J H |
| _timestamp | 2016-09-18 06:23:34 |
| created | [InstanceEdit:8939339] May, Bruce, 2016-09-18 |
| firstname | Richard J H |
| initial | RJ |
| surname | Wojcikiewicz |
| (author) | [LiteratureReference:8939337] RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation [LiteratureReference:8942154] Activated inositol 1,4,5-trisphosphate receptors are modified by homogeneous Lys-48- and Lys-63-linked ubiquitin chains, but only Lys-48-linked chains are required for degradation [LiteratureReference:8942479] A Point Mutation in the Ubiquitin Ligase RNF170 That Causes Autosomal Dominant Sensory Ataxia Destabilizes the Protein and Impairs Inositol 1,4,5-Trisphosphate Receptor-mediated Ca2+ Signaling |
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No pathways have been reviewed or authored by Wojcikiewicz, Richard J H (8939314)