Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person ESR dimerizes

Class:Id	Reaction:8939201
_displayName	ESR dimerizes
_doRelease	TRUE
_timestamp	2020-12-21 10:54:29
authored	[InstanceEdit:9024061] Rothfels, Karen, 2017-09-29
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8939206] Rothfels, Karen, 2016-09-16
edited	[InstanceEdit:9027686] Rothfels, Karen, 2017-11-03
input	[DefinedSet:9709550] ESR:ESTG [nucleoplasm] [Homo sapiens] [DefinedSet:9709550] ESR:ESTG [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8939266] Analysis of oestrogen receptor dimerisation using chimeric proteins [LiteratureReference:8939299] The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements [LiteratureReference:8939279] Dimerizing the estrogen receptor DNA binding domain enhances binding to estrogen response elements [LiteratureReference:8939302] The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer [LiteratureReference:8939275] Differential requirements of Hsp90 and DNA for the formation of estrogen receptor homodimers and heterodimers [LiteratureReference:8937304] Minireview: the intersection of steroid receptors with molecular chaperones: observations and questions [LiteratureReference:8937263] Breast cancer, estrogen receptor and ligands [LiteratureReference:8939288] Identification of estrogen-responsive genes based on the DNA binding properties of estrogen receptors using high-throughput sequencing technology [LiteratureReference:8939282] Estrogen receptor-mediated long-range chromatin interactions and transcription in breast cancer [LiteratureReference:9038047] Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor [LiteratureReference:9038143] Progesterone receptor modulates ERα action in breast cancer [LiteratureReference:9038268] A comprehensive nuclear receptor network for breast cancer cells [LiteratureReference:9038209] Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics [LiteratureReference:9038258] Enhancer activation requires trans-recruitment of a mega transcription factor complex [LiteratureReference:8937383] Chromatin and epigenetic determinants of estrogen receptor alpha (ESR1) signaling
modified	[InstanceEdit:8939303] Rothfels, Karen, 2016-09-16 [InstanceEdit:9024073] Rothfels, Karen, 2017-09-29 [InstanceEdit:9028385] Rothfels, Karen, 2017-11-07 [InstanceEdit:9029184] Rothfels, Karen, 2017-11-14 [InstanceEdit:9038171] Rothfels, Karen, 2018-02-23 [InstanceEdit:9038269] Rothfels, Karen, 2018-02-23 [InstanceEdit:9038275] Rothfels, Karen, 2018-02-23 [InstanceEdit:9709548] Jassal, Bijay, 2020-12-15 [InstanceEdit:9710005] Jassal, Bijay, 2020-12-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ESR dimerizes
output	[DefinedSet:9710004] ESR multimer:ESTG [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:8939203] HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex [Homo sapiens] [Reaction:8939204] ESTG binds ESR1:chaperone complex [Homo sapiens] [Reaction:9709547] ESTG binds ESR2:chaperone complex [Homo sapiens]
releaseDate	2018-03-21
reviewed	[InstanceEdit:9038169] Magnani, Luca, 2018-02-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8939207] R-HSA-8939201.3
summation	[Summation:8939200] Upon ligand binding, estrogen receptors form homo- or hetero...
(hasEvent)	[Pathway:8939211] ESR-mediated signaling [Homo sapiens]
(precedingEvent)	[Reaction:1254386] ERBB4s80 forms a complex with estrogen receptor ESR1 [Homo sapiens] [Reaction:8931981] RUNX1 binds ESR1 [Homo sapiens] [Reaction:8932070] ESR1 binds the AXIN1 gene [Homo sapiens] [Reaction:9009371] Binding of AP1 transcriptional activator complexes to CCND1 promoter [Homo sapiens] [Reaction:9011952] ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers [Homo sapiens] [Reaction:9011983] Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes [Homo sapiens] [Reaction:9011997] ESR1:ESTG, JUND:FOSB and Cohesin Complex bind distal enhancer elements in MYC gene promoter [Homo sapiens] [Reaction:9018325] ESR1:ESTG binds CXXC5 gene [Homo sapiens] [Reaction:9018499] ESR1:ESTG and EP300 are recruited to TFF3 promoter [Homo sapiens] [Reaction:9018503] ESR1:ESTG bind the EBAG9 5' region [Homo sapiens] List all 12 refering instances
(updatedInstance)	[_UpdateTracker:9776357] Update Tracker - [Reaction:8939201] ESR dimerizes - v76:[add_removeInput, add_removeOutput]
[Change default viewing format]

No pathways have been reviewed or authored by ESR dimerizes (8939201)