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Details on Person IL3 gene transcription is stimulated by RUNX1 and ELF1

Class:Id	BlackBoxEvent:8938981
_displayName	IL3 gene transcription is stimulated by RUNX1 and ELF1
_doRelease	TRUE
_timestamp	2017-05-09 14:03:53
authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
input	[EntityWithAccessionedSequence:8938941] IL3 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8938917] Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias
modified	[InstanceEdit:8941597] Orlic-Milacic, Marija, 2016-10-04 [InstanceEdit:9005630] Orlic-Milacic, Marija, 2017-05-09 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IL3 gene transcription is stimulated by RUNX1 and ELF1
output	[EntityWithAccessionedSequence:450059] IL3 [extracellular region] [Homo sapiens]
precedingEvent	[Reaction:8938938] RUNX1 and ELF1 bind the IL3 gene promoter [Homo sapiens] [Reaction:8938913] RUNX1 binds ELF1 [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:8938980] Positive gene expression regulation by 'RUNX1:CBFB:ELF1:IL3 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642463] Positive gene expression regulation by 'RUNX1:CBFB:ELF1:IL3 gene [nucleoplasm]' Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias
releaseDate	2017-06-12
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8938984] R-HSA-8938981.4
summation	[Summation:8938979] Binding of the RUNX1:CBFB complex associated with ELF1, an E...
(hasEvent)	[Pathway:8939247] RUNX1 regulates transcription of genes involved in interleukin signaling [Homo sapiens]
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No pathways have been reviewed or authored by IL3 gene transcription is stimulated by RUNX1 and ELF1 (8938981)