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Details on Person RUNX1:CBFB:ELF1,RUNX1:CBFB:ELF2,RUNX1:CBFB:PAX5 [nucleoplasm]
| Class:Id | DefinedSet:8938964 |
| _displayName | RUNX1:CBFB:ELF1,RUNX1:CBFB:ELF2,RUNX1:CBFB:PAX5 [nucleoplasm] |
| _timestamp | 2017-01-11 20:43:52 |
| compartment | [Compartment:7660] nucleoplasm |
| created | [InstanceEdit:8938967] Orlic-Milacic, Marija, 2016-09-14 |
| hasMember |
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| literatureReference | [LiteratureReference:8938917] Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias [LiteratureReference:8938906] Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene [LiteratureReference:8938950] AML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter |
| modified | [InstanceEdit:8955517] Orlic-Milacic, Marija, 2017-01-11 |
| name | RUNX1:CBFB:ELF1,RUNX1:CBFB:ELF2,RUNX1:CBFB:PAX5 |
| species | [Species:48887] Homo sapiens |
| stableIdentifier | [StableIdentifier:8938971] R-HSA-8938964.1 |
| (activeUnit) | [PositiveGeneExpressionRegulation:8938986] Positive gene expression regulation by 'RUNX1:CBFB:ELF,ELF2,PAX5:BLK gene [nucleoplasm]' |
| (hasComponent) | [Complex:8938969] RUNX1:CBFB:ELF,ELF2,PAX5:BLK gene [nucleoplasm] [Homo sapiens] |
| (input) | [Reaction:8938965] RUNX1 and ELF1, ELF2 or PAX5 bind the BLK gene promoter [Homo sapiens] |
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No pathways have been reviewed or authored by RUNX1:CBFB:ELF1,RUNX1:CBFB:ELF2,RUNX1:CBFB:PAX5 [nucleoplasm] (8938964)