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Details on Person AML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter

Class:IdLiteratureReference:8938950
_displayNameAML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter
_timestamp2016-09-14 15:20:28
author[Person:4608692] Libermann, T A
[Person:8938949] Pan, Z
[Person:8938954] Akbarali, Y
[Person:8938955] Hetherington, C J
[Person:8938952] Boltax, J
[Person:8938956] Yergeau, D A
[Person:8938953] Zhang, D E
created[InstanceEdit:8938947] Orlic-Milacic, Marija, 2016-09-14
journalJ. Biol. Chem.
pages24671-6
pubMedIdentifier10455134
titleAML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter
volume274
year1999
(literatureReference)[Complex:8938948] RUNX1:CBFB:PAX5 [nucleoplasm] [Homo sapiens]
[DefinedSet:8938964] RUNX1:CBFB:ELF1,RUNX1:CBFB:ELF2,RUNX1:CBFB:PAX5 [nucleoplasm] [Homo sapiens]
[Complex:8938969] RUNX1:CBFB:ELF,ELF2,PAX5:BLK gene [nucleoplasm] [Homo sapiens]
[RegulationReference:9642000] Positive gene expression regulation by 'RUNX1:CBFB:ELF,ELF2,PAX5:BLK gene [nucleoplasm]' Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene
[Reaction:8938951] RUNX1 binds PAX5 (BSAP) [Homo sapiens]
[Reaction:8938965] RUNX1 and ELF1, ELF2 or PAX5 bind the BLK gene promoter [Homo sapiens]
[BlackBoxEvent:8938987] BLK gene expression is stimulated by the complex of RUNX1 and ELF1, ELF2 or PAX5 [Homo sapiens]
[Pathway:8939245] RUNX1 regulates transcription of genes involved in BCR signaling [Homo sapiens]
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