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Details on Person RNF144A polyubiquitinates PRKDC

Class:IdBlackBoxEvent:8938773
_displayNameRNF144A polyubiquitinates PRKDC
_doReleaseTRUE
_timestamp2016-10-18 14:12:05
authored[InstanceEdit:8938762] May, Bruce, 2016-09-11
catalystActivity[CatalystActivity:8938764] ubiquitin protein ligase activity of RNF144A:PRKDC:Ub:UBE2L3 [cytosol]
catalystActivityReference[CatalystActivityReference:9643222] ubiquitin protein ligase activity of RNF144A:PRKDC:Ub:UBE2L3 [cytosol] RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage
compartment[Compartment:70101] cytosol
[Compartment:74700] endosome membrane
created[InstanceEdit:8938772] May, Bruce, 2016-09-11
edited[InstanceEdit:8938762] May, Bruce, 2016-09-11
input[Complex:8938767] RNF144A:PRKDC:Ub:UBE2L3 [cytosol] [Homo sapiens]
[Complex:8938763] Ub:UBE2L3 [cytosol] [Homo sapiens]
[Complex:8938763] Ub:UBE2L3 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:8938769] RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage
[LiteratureReference:8942122] Regulation of RNF144A E3 Ubiquitin Ligase Activity by Self-association through Its Transmembrane Domain
modified[InstanceEdit:8942163] May, Bruce, 2016-10-08
[InstanceEdit:8942557] May, Bruce, 2016-10-18
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRNF144A polyubiquitinates PRKDC
output[EntityWithAccessionedSequence:8938771] RNF144A [endosome membrane] [Homo sapiens]
[EntityWithAccessionedSequence:947631] UBE2L3 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:947631] UBE2L3 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:947631] UBE2L3 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:8938766] K48polyUb-PRKDC [cytosol] [Homo sapiens]
precedingEvent
releaseDate2016-12-12
reviewed[InstanceEdit:8942548] Lin, Weei-Chin, 2016-10-18
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8938777] R-HSA-8938773.3
summation[Summation:8942132] The ubiquitin E3 ligase RNF144A transfers ubiquitin from the...
(hasEvent)[Pathway:8866654] E3 ubiquitin ligases ubiquitinate target proteins [Homo sapiens]
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No pathways have been reviewed or authored by RNF144A polyubiquitinates PRKDC (8938773)