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Details on Person SERPINB13 gene expression is inhibited by RUNX1:CBFB

Class:Id	BlackBoxEvent:8938063
_displayName	SERPINB13 gene expression is inhibited by RUNX1:CBFB
_doRelease	TRUE
_timestamp	2017-05-09 14:04:04
authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
compartment	[Compartment:7660] nucleoplasm [Compartment:161320] lysosomal lumen
created	[InstanceEdit:8938062] Orlic-Milacic, Marija, 2016-09-08
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
input	[EntityWithAccessionedSequence:8938046] SERPINB13 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8938051] SERPINB13 is a novel RUNX1 target gene
modified	[InstanceEdit:8938072] Orlic-Milacic, Marija, 2016-09-08 [InstanceEdit:8941597] Orlic-Milacic, Marija, 2016-10-04 [InstanceEdit:8955747] Orlic-Milacic, Marija, 2017-01-13 [InstanceEdit:9005630] Orlic-Milacic, Marija, 2017-05-09 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SERPINB13 gene expression is inhibited by RUNX1:CBFB
output	[EntityWithAccessionedSequence:8938045] SERPINB13 [lysosomal lumen] [Homo sapiens]
precedingEvent	[Reaction:8938053] RUNX1:CBFB binds the SERPINB13 gene promoter [Homo sapiens] [Reaction:8865320] CBFB binds RUNX1 [Homo sapiens]
regulatedBy	[NegativeGeneExpressionRegulation:8938061] Negative gene expression regulation by 'RUNX1:CBFB:SERPINB13 gene [nucleoplasm]'
regulationReference	[RegulationReference:9641456] Negative gene expression regulation by 'RUNX1:CBFB:SERPINB13 gene [nucleoplasm]' SERPINB13 is a novel RUNX1 target gene
releaseDate	2017-06-12
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8938064] R-HSA-8938063.4
summation	[Summation:8938060] Binding of the RUNX1:CBFB complex to the promoter of the SER...
(hasEvent)	[Pathway:8939242] RUNX1 regulates transcription of genes involved in differentiation of keratinocytes [Homo sapiens]
(precedingEvent)	[Reaction:8938108] SERPINB13 binds cathepsin L [Homo sapiens] [Reaction:8938121] SERPINB13 binds CTSK [Homo sapiens]
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No pathways have been reviewed or authored by SERPINB13 gene expression is inhibited by RUNX1:CBFB (8938063)