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Details on Person RUNX2:CBFB:p-Y-YAP1 binds the BGLAP gene promoter

Class:Id	Reaction:8937869
_displayName	RUNX2:CBFB:p-Y-YAP1 binds the BGLAP gene promoter
_doRelease	TRUE
_timestamp	2017-08-09 17:09:57
authored	[InstanceEdit:8937870] Orlic-Milacic, Marija, 2016-09-07
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8937870] Orlic-Milacic, Marija, 2016-09-07
edited	[InstanceEdit:9015316] Orlic-Milacic, Marija, 2017-08-09
inferredFrom	[Reaction:8937949] Runx2:Cbfb:p-Y-Yap1 binds the Bglap gene promoter [Rattus norvegicus]
input	[Complex:8937863] RUNX2:CBFB:p-Y-YAP1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8877914] BGLAP gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:8937826] Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
modified	[InstanceEdit:8937953] Orlic-Milacic, Marija, 2016-09-07 [InstanceEdit:8952932] Orlic-Milacic, Marija, 2016-12-20 [InstanceEdit:9014260] Orlic-Milacic, Marija, 2017-07-27 [InstanceEdit:9015315] Orlic-Milacic, Marija, 2017-08-09 [InstanceEdit:9015316] Orlic-Milacic, Marija, 2017-08-09 [InstanceEdit:9015317] Orlic-Milacic, Marija, 2017-08-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX2:CBFB:p-Y-YAP1 binds the BGLAP gene promoter
output	[Complex:8937871] RUNX2:CBFB:p-Y-YAP1:BGLAP gene [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:8937864] RUNX2 binds tyrosine phosphorylated YAP1 [Homo sapiens] [Reaction:8937856] p-Y-YAP1 translocates to the nucleus [Homo sapiens] [Reaction:8865425] RUNX2 binds CBFB [Homo sapiens]
releaseDate	2017-09-12
reviewed	[InstanceEdit:9015314] Ducy, Patricia, 2017-08-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8937872] R-HSA-8937869.2
summation	[Summation:8937868] Based on studies in rat, the complex of RUNX2, presumably as...
(hasEvent)	[Pathway:8940973] RUNX2 regulates osteoblast differentiation [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8877922] BGLAP gene expression is stimulated by RUNX2, WWTR1 and RB1 and inhibited by AR, YAP1 and ZNF521 [Homo sapiens]
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No pathways have been reviewed or authored by RUNX2:CBFB:p-Y-YAP1 binds the BGLAP gene promoter (8937869)