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Details on Person CES3 hydrolyses CHEST to CHOL and LCFA(-)

Class:Id	Reaction:8937442
_displayName	CES3 hydrolyses CHEST to CHOL and LCFA(-)
_doRelease	TRUE
_timestamp	2017-02-16 16:15:33
authored	[InstanceEdit:8937436] Jassal, Bijay, 2016-09-01
catalystActivity	[CatalystActivity:8937438] carboxylic ester hydrolase activity of CES3 [cytosol]
compartment	[Compartment:70101] cytosol [Compartment:13977] lipid droplet [Compartment:13946] transport vesicle membrane
created	[InstanceEdit:8937436] Jassal, Bijay, 2016-09-01
edited	[InstanceEdit:8937436] Jassal, Bijay, 2016-09-01
input	[SimpleEntity:29356] H2O [cytosol] [SimpleEntity:163579] CHEST [lipid droplet]
isChimeric	FALSE
literatureReference	[LiteratureReference:8942489] Identification of a novel intracellular cholesteryl ester hydrolase (carboxylesterase 3) in human macrophages: compensatory increase in its expression after carboxylesterase 1 silencing [LiteratureReference:8942491] Mammalian carboxylesterase 3: comparative genomics and proteomics
modified	[InstanceEdit:8937446] Jassal, Bijay, 2016-09-01 [InstanceEdit:8937448] Jassal, Bijay, 2016-09-01 [InstanceEdit:8937460] Jassal, Bijay, 2016-09-02 [InstanceEdit:8942494] Jassal, Bijay, 2016-10-17 [InstanceEdit:8942498] Jassal, Bijay, 2016-10-17 [InstanceEdit:8942500] Jassal, Bijay, 2016-10-17 [InstanceEdit:8942501] Jassal, Bijay, 2016-10-17 [InstanceEdit:8964415] D'Eustachio, Peter, 2017-02-16 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CES3 hydrolyses CHEST to CHOL and LCFA(-)
output	[SimpleEntity:216762] CHOL [transport vesicle membrane] [SimpleEntity:8876730] LCFA(-) [cytosol]
releaseDate	2016-12-12
reviewed	[InstanceEdit:8942502] D'Eustachio, Peter, 2016-10-17
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8937445] R-HSA-8937442.3
summation	[Summation:8942496] In macrophage foam cells, the hydrolysis of cholesteryl este...
(hasEvent)	[Pathway:211945] Phase I - Functionalization of compounds [Homo sapiens] [Pathway:8964038] LDL clearance [Homo sapiens]
(precedingEvent)	[Reaction:216723] 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane [Homo sapiens]
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No pathways have been reviewed or authored by CES3 hydrolyses CHEST to CHOL and LCFA(-) (8937442)