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Details on Person AHR:TCDD binds ARNT

Class:IdReaction:8937177
_displayNameAHR:TCDD binds ARNT
_doReleaseTRUE
_timestamp2025-08-13 21:47:00
authored[InstanceEdit:8937178] Jassal, Bijay, 2016-08-30
catalystActivity[CatalystActivity:9958470] DNA-binding transcription activator activity, RNA polymerase II-specific of ARNT, ARNT2 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:8937178] Jassal, Bijay, 2016-08-30
edited[InstanceEdit:8937178] Jassal, Bijay, 2016-08-30
input[Complex:8937150] AHR:TCDD [nucleoplasm] [Homo sapiens]
[DefinedSet:8936837] ARNT, ARNT2 [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9958489] D'Eustachio, Peter, 2025-06-20
isChimericFALSE
literatureReference[LiteratureReference:8937174] Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt
modified[InstanceEdit:8942335] Jassal, Bijay, 2016-10-13
[InstanceEdit:8942336] Jassal, Bijay, 2016-10-13
[InstanceEdit:8942338] Jassal, Bijay, 2016-10-13
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9958472] D'Eustachio, Peter, 2025-06-20
[InstanceEdit:9958488] D'Eustachio, Peter, 2025-06-20
[InstanceEdit:9963237] D'Eustachio, Peter, 2025-08-13
nameAHR:TCDD binds ARNT
output[Complex:8937203] AHR:TCDD:ARNT [nucleoplasm] [Homo sapiens]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2016-12-12
reviewed[InstanceEdit:8942222] D'Eustachio, Peter, 2016-10-11
[InstanceEdit:9963238] Hill, David P, 2025-08-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8937213] R-HSA-8937177.3
structureModified[InstanceEdit:9958472] D'Eustachio, Peter, 2025-06-20
summation[Summation:8937171] Ligand-bound aryl hydrocarbon receptor (AHR:TCDD) disassocia...
(hasEvent)[Pathway:8937144] Aryl hydrocarbon receptor signalling [Homo sapiens]
(updatedInstance)[_UpdateTracker:9964697] Update Tracker - [Reaction:8937177] AHR:TCDD binds ARNT - v94:[removeCatalystActivity]
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No pathways have been reviewed or authored by AHR:TCDD binds ARNT (8937177)