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Details on Person AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm

Class:IdReaction:8937169
_displayNameAHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm
_doReleaseTRUE
_timestamp2025-08-13 21:47:02
authored[InstanceEdit:8937178] Jassal, Bijay, 2016-08-30
catalystActivity[CatalystActivity:9958474] nuclear receptor activity of AHR:TCDD:2xHSP90AB1:AIP:PTGES3 [cytosol]
catalystActivityReference[CatalystActivityReference:9958469] nuclear receptor activity of AHR:TCDD:2xHSP90AB1:AIP:PTGES3 [cytosol] The hsp90 chaperone complex regulates intracellular localization of the dioxin receptor
compartment[Compartment:70101] cytosol
[Compartment:7660] nucleoplasm
created[InstanceEdit:8937178] Jassal, Bijay, 2016-08-30
edited[InstanceEdit:8937178] Jassal, Bijay, 2016-08-30
input[Complex:8936846] AHR:TCDD:2xHSP90AB1:AIP:PTGES3 [cytosol] [Homo sapiens]
internalReviewed[InstanceEdit:9958489] D'Eustachio, Peter, 2025-06-20
isChimericFALSE
literatureReference[LiteratureReference:8937206] The aryl hydrocarbon receptor complex and the control of gene expression
[LiteratureReference:8937158] The hsp90 chaperone complex regulates intracellular localization of the dioxin receptor
modified[InstanceEdit:8942335] Jassal, Bijay, 2016-10-13
[InstanceEdit:8942336] Jassal, Bijay, 2016-10-13
[InstanceEdit:8942338] Jassal, Bijay, 2016-10-13
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9958472] D'Eustachio, Peter, 2025-06-20
[InstanceEdit:9958488] D'Eustachio, Peter, 2025-06-20
[InstanceEdit:9963237] D'Eustachio, Peter, 2025-08-13
nameAHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm
output[Complex:8937154] AHR:TCDD:2xHSP90AB1:AIP:PTGES3 [nucleoplasm] [Homo sapiens]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2016-12-12
reviewed[InstanceEdit:8942222] D'Eustachio, Peter, 2016-10-11
[InstanceEdit:9963238] Hill, David P, 2025-08-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8937215] R-HSA-8937169.3
structureModified[InstanceEdit:9958472] D'Eustachio, Peter, 2025-06-20
summation[Summation:8937209] After ligand binding and activation, the AHR complex translo...
(hasEvent)[Pathway:8937144] Aryl hydrocarbon receptor signalling [Homo sapiens]
(updatedInstance)[_UpdateTracker:9964709] Update Tracker - [Reaction:8937169] AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm - v94:[removeCatalystActivity]
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