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Details on Person Jaiswal, Anil K

Class:Id	Person:8936794
_displayName	Jaiswal, Anil K
_timestamp	2016-08-24 09:16:38
created	[InstanceEdit:8936790] Jassal, Bijay, 2016-08-24
firstname	Anil K
initial	AK
surname	Jaiswal
(author)	[LiteratureReference:8936775] NRH:quinone oxidoreductase 2 (NQO2) catalyzes metabolic activation of quinones and anti-tumor drugs [LiteratureReference:9708555] Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression [LiteratureReference:9795391] Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis [LiteratureReference:9795410] An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance [LiteratureReference:9795456] Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance
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No pathways have been reviewed or authored by Jaiswal, Anil K (8936794)