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Details on Person phosphorylated moderate kinase activity BRAF mutants [plasma membrane]

Class:Id	CandidateSet:8936658
_displayName	phosphorylated moderate kinase activity BRAF mutants [plasma membrane]
_timestamp	2019-08-06 17:26:43
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:8936657] Rothfels, Karen, 2016-08-22
disease	[Disease:1500689] cancer [Disease:9651119] cardiofaciocutaneous syndrome
hasCandidate	[EntityWithAccessionedSequence:9648633] p-BRAF G464V [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9648629] p-BRAF G466A [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9648859] p-BRAF G466V [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9648634] p-BRAF G469E [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9648627] p-BRAF G469R [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9648628] p-BRAF G469V [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9648630] p-BRAF L597Q [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9648631] p-BRAF L597R [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9648866] p-BRAF N581S [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9651194] p-BRAF T244P [plasma membrane] [Homo sapiens]
hasMember	[EntityWithAccessionedSequence:8936639] p-BRAF E586K [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8936641] p-BRAF F595L [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8936645] p-BRAF G464E [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8936647] p-BRAF L597V [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:8936651] p-BRAF V600K [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9648862] p-BRAF L505H [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9651191] p-BRAF N581D [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:9651188] p-BRAF A246P [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:5672236] Mutations of the BRAF gene in human cancer [LiteratureReference:5672469] Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF [LiteratureReference:9651037] Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome
modified	[InstanceEdit:9648643] Rothfels, Karen, 2019-06-07 [InstanceEdit:9648870] Rothfels, Karen, 2019-06-07 [InstanceEdit:9649001] Rothfels, Karen, 2019-06-10 [InstanceEdit:9651210] Rothfels, Karen, 2019-06-25 [InstanceEdit:9657036] Rothfels, Karen, 2019-08-06
name	phosphorylated moderate kinase activity BRAF mutants
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8936659] R-HSA-8936658.2
(hasComponent)	[Complex:8936663] phosphorylated moderate kinase activity BRAF mutants:YWHAB [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by phosphorylated moderate kinase activity BRAF mutants [plasma membrane] (8936658)