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Details on Person Diagram of RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
| Class:Id | PathwayDiagram:8936458 |
|---|---|
| _displayName | Diagram of RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function |
| _timestamp | 2023-02-21 13:12:53 |
| created | [InstanceEdit:8936460] Orlic-Milacic, Marija, 2016-08-19 |
| height | 1337 |
| modified | [InstanceEdit:8936475] Orlic-Milacic, Marija, 2016-08-19 [InstanceEdit:8936476] Orlic-Milacic, Marija, 2016-08-19 [InstanceEdit:8936480] Orlic-Milacic, Marija, 2016-08-19 [InstanceEdit:8936490] Orlic-Milacic, Marija, 2016-08-19 [InstanceEdit:8936590] Orlic-Milacic, Marija, 2016-08-22 [InstanceEdit:8936604] Orlic-Milacic, Marija, 2016-08-22 [InstanceEdit:8936612] Orlic-Milacic, Marija, 2016-08-22 [InstanceEdit:8936619] Orlic-Milacic, Marija, 2016-08-22 [InstanceEdit:8936627] Orlic-Milacic, Marija, 2016-08-22 [InstanceEdit:8936631] Orlic-Milacic, Marija, 2016-08-22 [InstanceEdit:8936637] Orlic-Milacic, Marija, 2016-08-22 [InstanceEdit:8936653] Orlic-Milacic, Marija, 2016-08-22 [InstanceEdit:8936985] Orlic-Milacic, Marija, 2016-08-25 [InstanceEdit:8936992] Orlic-Milacic, Marija, 2016-08-25 [InstanceEdit:8936999] Orlic-Milacic, Marija, 2016-08-25 [InstanceEdit:8937005] Orlic-Milacic, Marija, 2016-08-25 [InstanceEdit:8937009] Orlic-Milacic, Marija, 2016-08-26 [InstanceEdit:8937019] Orlic-Milacic, Marija, 2016-08-26 [InstanceEdit:8937027] Orlic-Milacic, Marija, 2016-08-26 [InstanceEdit:8937046] Orlic-Milacic, Marija, 2016-08-26 [InstanceEdit:8937047] Orlic-Milacic, Marija, 2016-08-26 [InstanceEdit:8937055] Orlic-Milacic, Marija, 2016-08-26 [InstanceEdit:8937124] Orlic-Milacic, Marija, 2016-08-29 [InstanceEdit:8937129] Orlic-Milacic, Marija, 2016-08-29 [InstanceEdit:8937130] Orlic-Milacic, Marija, 2016-08-29 [InstanceEdit:8937131] Orlic-Milacic, Marija, 2016-08-29 [InstanceEdit:8938193] Orlic-Milacic, Marija, 2016-09-08 [InstanceEdit:8938194] Orlic-Milacic, Marija, 2016-09-08 [InstanceEdit:8939239] Orlic-Milacic, Marija, 2016-09-16 [InstanceEdit:8939609] Orlic-Milacic, Marija, 2016-09-20 [InstanceEdit:8955516] Orlic-Milacic, Marija, 2017-01-11 [InstanceEdit:9006679] Orlic-Milacic, Marija, 2017-05-17 [InstanceEdit:9697617] Orlic-Milacic, Marija, 2020-08-18 [InstanceEdit:9829014] Orlic-Milacic, Marija, 2023-02-21 |
| representedPathway | [Pathway:8936459] RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function [Homo sapiens] |
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<org.gk.render.RenderableProtein id="1903" reactomeId="390753" position="488 1254" bounds="468 1243 40 22" textPosition="468 1243"> <Properties> <displayName>MYL9</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableGene id="1905" reactomeId="8938324" position="552 863" bounds="527 838 50 51" textPosition="531 865"> <Properties> <displayName>NFE2 gene</displayName> </Properties> </org.gk.render.RenderableGene> <org.gk.render.RenderableComplex id="1906" reactomeId="8938329" position="701 1058" bounds="657 1040 88 36" textPosition="658 1041" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>RUNX1:CBFB:NFE2 gene</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableProtein id="1908" reactomeId="1008221" position="621 1149" bounds="602 1138 39 22" textPosition="602 1138"> <Properties> <displayName>NFE2</displayName> </Properties> </org.gk.render.RenderableProtein> </Nodes> <Edges> <org.gk.render.RenderableReaction id="10" reactomeId="8934742" points="307 421, 315 445, 315 480" position="315 445" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="11" points="307 342" /> <Input id="12" points="483 426" /> </Inputs> <Outputs> <Output id="13" /> </Outputs> <Properties> <displayName>RUNX1 binds PRMT1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="14" reactomeId="8934735" points="321 550, 323 586, 326 613" position="323 586" lineWidth="1.0"> <Inputs> <Input id="15" stoichiometry="2" points="273 549" /> <Input id="13" points="317 520" /> </Inputs> <Outputs> <Output id="16" stoichiometry="2" points="272 616" /> <Output id="17" points="322 652" /> </Outputs> <Catalysts> <Catalyst id="13" points="329 520, 359 552" /> </Catalysts> <Properties> <displayName>PRMT1 arginine-methylates RUNX1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="18" reactomeId="8935740" points="979 822, 991 812, 1012 808" position="991 812" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="179" points="897 680" /> <Input id="19" points="814 857" /> <Input id="169" points="795 792" /> <Input id="170" points="759 723" /> <Input id="138" points="719 598" /> <Input id="178" points="960 690" /> <Input id="22" points="1011 496" /> </Inputs> <Outputs> <Output id="23" /> </Outputs> <Properties> <displayName>RUNX1 and GATA1 bind the promoter of the ITGA2B gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="20" points="368 700, 692 839" position="530 769" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="17" /> </Inputs> <Outputs> <Output id="19" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="21" points="532 442, 736 839" position="634 640" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="12" /> </Inputs> <Outputs> <Output id="19" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="24" reactomeId="8935731" points="1011 496, 1535 571, 1973 498" position="1535 571" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="22" /> </Inputs> <Outputs> <Output id="25" /> </Outputs> <Inhibitors> <Inhibitor id="568" points="1537 510" /> </Inhibitors> <Activators> <Activator id="296" points="1526 748" /> </Activators> <Properties> <displayName>ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="27" reactomeId="8935732" points="676 428, 674 355, 735 354" position="674 355" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="28" points="746 459" /> <Input id="29" points="652 450" /> <Input id="30" points="714 495" /> <Input id="12" points="571 428" /> </Inputs> <Outputs> <Output id="31" /> </Outputs> <Inhibitors> <Inhibitor id="11" points="335 329" /> </Inhibitors> <Properties> <displayName>RUNX1 binds SIN3A,(SIN3B) co-repressor</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="39" reactomeId="8935730" points="865 459, 934 456, 1017 460" position="934 456" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="22" points="1011 496" /> <Input id="31" points="820 376" /> <Input id="138" points="724 556" /> </Inputs> <Outputs> <Output id="26" /> </Outputs> <Properties> <displayName>RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the ITGA2B promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="295" reactomeId="8936481" points="1303 795, 1336 796, 1375 798" position="1336 796" lineWidth="1.0"> <Inputs> <Input id="23" points="1249 793" /> <Input id="298" stoichiometry="2" points="1289 827" /> </Inputs> <Outputs> <Output id="296" points="1402 795" /> <Output id="297" stoichiometry="2" points="1392 836" /> </Outputs> <Catalysts> <Catalyst id="23" points="1249 769, 1295 760" /> </Catalysts> <Properties> <displayName>Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="567" reactomeId="8936584" points="1273 470, 1333 467, 1393 474" position="1333 467" lineWidth="1.0"> <Inputs> <Input id="26" points="1211 468" /> <Input id="572" stoichiometry="4" points="1268 435" /> </Inputs> <Outputs> <Output id="568" points="1425 475" /> <Output id="570" stoichiometry="4" points="1401 439" /> </Outputs> <Catalysts> <Catalyst id="26" points="1199 494, 1239 502" /> </Catalysts> <Properties> <displayName>PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="686" reactomeId="8936599" points="843 449, 934 433, 1010 414" position="934 433" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="687" points="913 560" /> <Input id="31" points="817 376" /> <Input id="138" points="719 556" /> </Inputs> <Outputs> <Output id="688" /> </Outputs> <Properties> <displayName>RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the GP1BA promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="753" reactomeId="8936608" points="1248 364, 1326 376, 1388 364" position="1326 376" lineWidth="1.0"> <Inputs> <Input id="688" points="1192 376" /> <Input id="572" stoichiometry="4" points="1261 399" /> </Inputs> <Outputs> <Output id="754" points="1524 367" /> <Output id="570" stoichiometry="4" points="1400 403" /> </Outputs> <Catalysts> <Catalyst id="688" points="1172 363, 1231 342" /> </Catalysts> <Properties> <displayName>PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="825" reactomeId="8936616" points="938 863, 977 859, 1030 876" position="977 859" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="179" points="893 680" /> <Input id="687" points="913 560" /> <Input id="19" points="814 867" /> <Input id="170" points="745 723" /> <Input id="138" points="714 598" /> <Input id="178" points="957 690" /> <Input id="169" points="795 801" /> </Inputs> <Outputs> <Output id="832" /> </Outputs> <Properties> <displayName>RUNX1 and GATA1 bind the promoter of the GP1BA gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="884" reactomeId="8936621" points="1306 913, 1344 916, 1390 914" position="1344 916" lineWidth="1.0"> <Inputs> <Input id="832" points="1246 913" /> <Input id="298" stoichiometry="2" points="1288 863" /> </Inputs> <Outputs> <Output id="885" points="1506 920" /> <Output id="297" stoichiometry="2" points="1396 872" /> </Outputs> <Catalysts> <Catalyst id="832" points="1246 937, 1314 952" /> </Catalysts> <Properties> <displayName>Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="983" reactomeId="8936628" points="913 560, 1723 618, 2003 558" position="1723 618" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="687" /> </Inputs> <Outputs> <Output id="984" /> </Outputs> <Inhibitors> <Inhibitor id="754" points="1645 402" /> </Inhibitors> <Activators> <Activator id="885" points="1636 890" /> </Activators> <Properties> <displayName>GP1BA gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1064" reactomeId="8936979" points="909 867, 952 976, 999 987" position="952 976" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="170" points="742 723" /> <Input id="179" points="892 680" /> <Input id="178" points="956 690" /> <Input id="169" points="795 804" /> <Input id="138" points="712 598" /> <Input id="1065" points="842 588" /> <Input id="19" points="814 868" /> </Inputs> <Outputs> <Output id="1066" /> </Outputs> <Properties> <displayName>RUNX1 and GATA1 bind the promoter of the THBS1 gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1124" reactomeId="8936989" points="885 478, 931 342, 1010 320" position="931 342" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="138" points="732 556" /> <Input id="1065" points="842 588" /> <Input id="31" points="822 376" /> </Inputs> <Outputs> <Output id="1125" /> </Outputs> <Properties> <displayName>RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the THBS1 gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1242" reactomeId="8936995" points="842 588, 862 636, 1770 701, 1895 824" position="1770 701" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="1065" /> </Inputs> <Outputs> <Output id="1243" /> </Outputs> <Inhibitors> <Inhibitor id="1412" points="1753 285, 1778 287" /> </Inhibitors> <Activators> <Activator id="1311" points="1724 1020, 1759 1021" /> </Activators> <Properties> <displayName>THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1310" reactomeId="8937016" points="1272 1005, 1378 1014, 1442 1013" position="1378 1014" lineWidth="1.0"> <Inputs> <Input id="1066" points="1239 1006" /> <Input id="298" stoichiometry="2" points="1281 863" /> </Inputs> <Outputs> <Output id="1311" points="1490 1014" /> <Output id="297" stoichiometry="2" points="1403 872" /> </Outputs> <Catalysts> <Catalyst id="1066" points="1239 1029, 1326 1043" /> </Catalysts> <Properties> <displayName>Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1420" reactomeId="8937022" points="1289 295, 1353 292, 1406 294" position="1353 292" lineWidth="1.0"> <Inputs> <Input id="1125" points="1193 296" /> <Input id="572" stoichiometry="4" points="1269 399" /> </Inputs> <Outputs> <Output id="1412" points="1528 286" /> <Output id="570" stoichiometry="4" points="1405 403" /> </Outputs> <Catalysts> <Catalyst id="1125" points="1178 271, 1275 244" /> </Catalysts> <Properties> <displayName>PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1528" reactomeId="8937037" points="960 921, 970 1044, 1038 1068" position="970 1044" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="170" points="741 723" /> <Input id="179" points="894 680" /> <Input id="178" points="959 690" /> <Input id="138" points="712 598" /> <Input id="169" points="787 810" /> <Input id="19" points="814 884" /> <Input id="1529" points="989 580" /> </Inputs> <Outputs> <Output id="1530" /> </Outputs> <Properties> <displayName>RUNX1 and GATA1 bind the promoter of the MIR27A gene</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1585" reactomeId="8937050" points="1298 1112, 1362 1116, 1430 1100" position="1362 1116" lineWidth="1.0"> <Inputs> <Input id="1530" points="1240 1108" /> <Input id="298" stoichiometry="2" points="1283 863" /> </Inputs> <Outputs> <Output id="1586" points="1487 1101" /> <Output id="297" stoichiometry="2" points="1400 872" /> </Outputs> <Catalysts> <Catalyst id="1530" points="1212 1137, 1270 1153" /> </Catalysts> <Properties> <displayName>Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1781" reactomeId="8937118" points="882 455, 930 227, 991 220" position="930 227" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1529" points="989 580, 915 547" /> <Input id="31" points="824 376" /> <Input id="138" points="726 556" /> </Inputs> <Outputs> <Output id="1782" /> </Outputs> <Properties> <displayName>RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the MIR27A gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1783" reactomeId="8937113" points="1246 215, 1341 207, 1432 231" position="1341 207" lineWidth="1.0"> <Inputs> <Input id="1782" points="1184 213" /> <Input id="572" stoichiometry="4" points="1265 399" /> </Inputs> <Outputs> <Output id="1784" points="1526 218" /> <Output id="570" stoichiometry="4" points="1407 403" /> </Outputs> <Catalysts> <Catalyst id="1782" points="1184 190, 1241 177" /> </Catalysts> <Properties> <displayName>PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1806" reactomeId="8937097" points="989 580, 1794 652, 1852 641" position="1794 652" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="1529" /> </Inputs> <Outputs> <Output id="1807" /> </Outputs> <Inhibitors> <Inhibitor id="1784" points="1747 203, 1798 203" /> </Inhibitors> <Activators> <Activator id="1586" points="1728 1099, 1785 1096" /> </Activators> <Properties> <displayName>MIR27A gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableInteraction id="1832" interactionType="Activate" points="1917 657, 1917 676" position="1917 666" lineWidth="2.0"> <Inputs> <Input id="1807" /> </Inputs> <Outputs> <Output id="1831" /> </Outputs> </org.gk.render.RenderableInteraction> <org.gk.render.RenderableReaction id="1884" reactomeId="8938176" points="712 992, 798 1024, 844 1039" position="798 1024" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1885" points="835 1111" /> <Input id="12" points="530 442" /> </Inputs> <Outputs> <Output id="1886" /> </Outputs> <Properties> <displayName>RUNX1:CBFB binds the PF4 gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1887" reactomeId="8938174" points="835 1111, 949 1155, 1854 1174, 1921 915" position="949 1155" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="1885" /> </Inputs> <Outputs> <Output id="1888" /> </Outputs> <Activators> <Activator id="1886" points="900 1075" /> </Activators> <Properties> <displayName>PF4 gene transcription is stimulated by RUNX1:CBFB</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1889" reactomeId="8938022" points="401 774, 388 805, 360 844" position="388 805" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1890" points="279 745" /> <Input id="12" points="522 442" /> </Inputs> <Outputs> <Output id="1891" /> </Outputs> <Properties> <displayName>RUNX1:CBFB binds the NR4A3 gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1892" reactomeId="8938034" points="279 745, 271 865, 271 930" position="271 865" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="1890" /> </Inputs> <Outputs> <Output id="1893" /> </Outputs> <Activators> <Activator id="1891" points="300 864" /> </Activators> <Properties> <displayName>NR4A3 gene expression is stimulated by RUNX1:CBFB</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1894" reactomeId="8938150" points="422 917, 426 1001, 428 1070" position="426 1001" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="1895" points="348 969" /> <Input id="12" points="524 442" /> </Inputs> <Outputs> <Output id="1896" /> </Outputs> <Properties> <displayName>RUNX1:CBFB binds the PRKCQ gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1897" reactomeId="8938158" points="348 969, 341 1088, 324 1243" position="341 1088" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="1895" /> </Inputs> <Outputs> <Output id="1898" /> </Outputs> <Activators> <Activator id="1896" points="377 1089" /> </Activators> <Properties> <displayName>PRKCQ gene expression is stimulated by RUNX1:CBFB</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1899" reactomeId="8938199" points="506 842, 530 924, 554 988" position="530 924" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="12" points="526 442" /> <Input id="1900" points="497 885" /> </Inputs> <Outputs> <Output id="1901" /> </Outputs> <Properties> <displayName>RUNX1:CBFB binds the MYL9 gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1902" reactomeId="8938201" points="497 885, 493 1013, 488 1240" position="493 1013" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="1900" /> </Inputs> <Outputs> <Output id="1903" /> </Outputs> <Activators> <Activator id="1901" points="516 1012" /> </Activators> <Properties> <displayName>MYL9 gene transcription is stimulated by RUNX1:CBFB</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1904" reactomeId="8938328" points="628 912, 672 992, 693 1037" position="672 992" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="12" points="529 442" /> <Input id="1905" points="586 840" /> </Inputs> <Outputs> <Output id="1906" /> </Outputs> <Properties> <displayName>RUNX1:CBFB binds the NFE2 gene promoter</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="1907" reactomeId="8938338" points="586 840, 624 1052, 621 1135" position="624 1052" lineWidth="1.0" reactionType="Omitted Process"> <Inputs> <Input id="1905" /> </Inputs> <Outputs> <Output id="1908" /> </Outputs> <Activators> <Activator id="1906" points="654 1054" /> </Activators> <Properties> <displayName>NFE2 gene expression is stimulated by RUNX1:CBFB</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process> |
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No pathways have been reviewed or authored by Diagram of RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (8936458)
