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Details on Person Jupe, S, 2010-07-01
| Class:Id | InstanceEdit:893547 |
| _displayName | Jupe, S, 2010-07-01 |
| _timestamp | 2010-07-01 16:57:01 |
| author | [Person:391309] Jupe, Steve |
| dateTime | 2010-07-01 20:55:55 |
| (created) | [Person:893509] Lucet, IS [Person:893510] Treutlein, H [Person:893511] Mui, AL [Person:893512] Terada, N [LiteratureReference:893513] Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors [Person:893514] Dusa, A [LiteratureReference:893515] Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signaling [Person:893516] Rosario, F [Person:893517] Broughton, SE [Person:893518] Patel, O |
| (modified) | [EntityWithAccessionedSequence:205921] Jak2 [plasma membrane] [Mus musculus] [Reaction:879907] Tyrosine kinases phosphorylate the receptor [Homo sapiens] [Reaction:879910] JAK2 is phosphorylated, activated [Homo sapiens] [Summation:879913] The interaction of IL-3 with the receptor leads to the activ... [Reaction:879937] The common beta chain IL3RB binds JAK2 [Homo sapiens] [BlackBoxEvent:879942] The receptor is activated [Homo sapiens] [Summation:879946] Upon ligand binding to the alpha subunit, the alpha and Bc s... [Summation:879955] JAK2 is tyrosine phosphorylated in response to IL-3 (Silvenn... [ModifiedResidue:879963] O4'-phospho-L-tyrosine at 1007 |
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No pathways have been reviewed or authored by Jupe, S, 2010-07-01 (893547)