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Details on Person UniProt:Q9VNZ8 Als2
| Class:Id | ReferenceGeneProduct:8934941 |
|---|---|
| _chainChangeLog | chain:1-1486 added on Fri August 12 2016 |
| _displayName | UniProt:Q9VNZ8 Als2 |
| _timestamp | 2023-11-03 16:18:17 |
| chain | chain:1-1486 |
| checksum | C46DF7E7928E1204 |
| comment | FUNCTION Has guanine nucleotide exchange factor (GEF) activity towards Rab5. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab5 into its active GTP-bound form.TISSUE SPECIFICITY In the embryo, expressed in a wide range of tissues including the epidermis and the ventral nerve cord.DISRUPTION PHENOTYPE Deterioration of locomotion in adults with climbing ability strongly depressed. |
| created | [InstanceEdit:8934940] Weiser, JD |
| description | recommendedName: fullName evidence="5"Alsin homolog alternativeName: fullName evidence="4"Amyotrophic lateral sclerosis 2 protein homolog |
| geneName | Als2 CG7158 |
| identifier | Q9VNZ8 |
| isSequenceChanged | FALSE |
| keyword | GTPase activation Guanine-nucleotide releasing factor Reference proteome Repeat |
| modified | [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | Als2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | ALS2_DROME |
| sequenceLength | 1486 |
| species | [Species:56210] Drosophila melanogaster |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9VNZ8 Als2 (8934941)
