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Details on Person SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane

Class:Id	Reaction:8932980
_displayName	SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane
_doRelease	TRUE
_timestamp	2024-11-26 00:03:40
authored	[InstanceEdit:8932977] Jassal, Bijay, 2016-08-01
catalystActivity	[CatalystActivity:8932974] molecular carrier activity of SERINC3,5,(1,2,4) [plasma membrane]
catalystActivityReference	[CatalystActivityReference:9929430] molecular carrier activity of SERINC3,5,(1,2,4) [plasma membrane] Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:8932977] Jassal, Bijay, 2016-08-01
edited	[InstanceEdit:8932977] Jassal, Bijay, 2016-08-01
input	[SimpleEntity:200736] L-Ser [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:8932975] Spotlight on HIV-1 Nef: SERINC3 and SERINC5 Identified as Restriction Factors Antagonized by the Pathogenesis Factor [LiteratureReference:9929427] Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis [LiteratureReference:8932976] SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef
modified	[InstanceEdit:8932988] Jassal, Bijay, 2016-08-01 [InstanceEdit:8934578] Jassal, Bijay, 2016-08-11 [InstanceEdit:8934768] Jassal, Bijay, 2016-08-12 [InstanceEdit:8934769] Jassal, Bijay, 2016-08-12 [InstanceEdit:8935685] Jassal, Bijay, 2016-08-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9929424] D'Eustachio, Peter, 2024-11-26
name	SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane
output	[SimpleEntity:8932979] L-Ser [plasma membrane]
precedingEvent	[Reaction:977324] PSPH:Mg2+ dimer dephosphorylates O-P-Ser [Homo sapiens] [Reaction:977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA [Homo sapiens]
releaseDate	2016-09-19
reviewed	[InstanceEdit:8934767] D'Eustachio, Peter, 2016-08-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8932984] R-HSA-8932980.3
summation	[Summation:8932983] Serine incorporators 1-5 (SERINC1-5) are membrane-associated...
(hasEvent)	[Pathway:977347] Serine metabolism [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9939654] Update Tracker - [Reaction:8932980] SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane - v92:[modifyText, removeLiteratureReference]
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